The Analysis Of The Reagularity Of Treating Diabetes With "KuSuanZhiTian" Method On The Basis Of Clinic Data Mining

Diabetes is a kind of serious and chronic disease. The increasing incidence of diabetes every year has caught extensive attention of the whole society. Tight control of blood sugar is always the key to the treatment of diabetes. However, compared with western medicine, the advantage of TCM in treating diabetes is still improving symptoms of complications. There has never been any important breakthrough in controlling blood sugar with TCM. And it has influenced the improvement and approval of clinical effect of TCM.Pro Tong xiaolin finds that Xiaoke in ancient times is different from modern diabetes, according to his clinical experience and the related statements in the classical ancient book, and summarizes the pathogenesis and the development law of course of diabetes. On the basis of these new acknowledements, Pro Tong formulates the therapeutic method of "KuSuanZhiTian" in threating diabetes for the first time according to the natural law that bitterness and sour taste is the opposition of sweetness and the related theory of character and taste in Yellow Emperor's Internal Classic.This therapeutic method not only aims at the pathogenesis of diabetes characterized by fire evil, but also aims at the hyperglycemia. It can also comprehensively regulate the blood lipid, the blood pressure, the body weight, etc. which can influence the control of blood sugar.On the basis of previous animal experiments that has proved the effectiveness and scientificalness of "KuSuanZhiTian" in threating diabetes, the specialized Microsoft database of diabetes was constructed, medical records of Guang'anmen Hospital Chian Academy of TCM were collected and input into the database. With the decrease of glycosylation hemoglobinAlc(HbAlc) by 0.4%, or fasting blood glucose(FBG) by lmmol/L being as the criteria of evaluation, a total of 1321(amount to 3021 man-time)medical records were selected. And 945(amount to 1886 man-time)who have been treated with KuSuanZhiTian medical pairs were finally selected. Then all the data were analyzed with the data mining methods based on cluster ananlysis, association rules, scale-free network, etc. According to the analysis results, we summarized the characters of symptoms and syndrome, the relation with courses of dibetes, and the regularities of dosage of KuSuanZhiTian medical pairs usually used by Pro Tong in clinc. Through this method, Pro Tong's individual experience was upgraded to a treatment theory which can be popularized in clinic and useful for the treatment of diabetes and development of new drugs of TCM.