| ObjectiveAs the incidence of type 2 diabetes increases day by day and the hazards of its complications to people's life are worsening, early prevention and treatment of type 2 diabetes get more and more attention. Impaired glucose regulation is an important early stage of the development of type 2 diabetes. From the etiology and mechanism, secondary prevention to intervent impaired glucose regulation from diabetes and block the progress of diabetes will have practical significance and far-reaching impact of the prevention of diabetes and its complications.Professor Fan has rich clinical experience of treating diabetes. Previous studies have shown that Chinese medicine can delay the development of impaired glucose tolerance to type 2 diabetes, so that impaired glucose tolerance patients can return to healthy people. The purpose of this study is to explore Professor Fan's clinical dialectics methods and medication rules in order to search for a safe and effective prevention program for impaired glucose regulation and type 2 diabetes patients.MethodThis study used retrospective analysis method of medical research with the application of SPSS 13.0 software for data analysis and processing. Four diagnostic information of impaired glucose regulation and type 2 diabetes patients'was collected to conduct frequency statistics and descriptive analysis of symptoms, tongues, pulses, syndromes, therapies and medicines. Divided into three periods (first visit,4 weeks return visit,12 weeks return visit), this study summarized the evolution law of syndrome. At the end it analyzed the characteristics and locations of the disease and medication rules. Results31 in 100 patients took hypoglycemic medicines when first visit. After 3 to 6 months treatment they stoped them. After 3 months pure Chinese medicine treatment,17 type 2 diabetes turned to impaired glucose tolerance(22.1%).11 type 2 diabetes returned to normal glucose tolerance (14.3%).11 impaired glucose tolerance returned to normal glucose tolerance (64.7%).The "dry mouth" and "lassitude" arranged at the top of symptoms rank. "Irritability" and "wiry pulse" might be the main syndrome factors for Professor Fan to determine liver stagnation syndrome. "Soreness of the lumbus" and "faint and thready pulse" might be the main syndrome factors of kidney deficiency syndrome.At the medicine rank, Gancao was the first and Shengdi was the second. Mianyinchen which ranked the third was uesd as a unique medicine by Professor Fan. "Caihu, Baishao and Bohe" appeared almost at the same time, which were used as the common "Yaochuan" by Professor Fan to course the liver. "Gouji, Chuanduan, Nvzhenzi and Hanliancao" were the common "Yaochuan" to supplement the kidney.Qi and Yin deficiency was the most common syndrome in clinical, followed by liver stagnation syndrome, blood stasis syndrome and kidney difficiency syndrome, respectively accounted for 50%,42% and 35%. Syndromes were complex, 3 patterns were mostly common, followed by 2 patterns and 4 patterns. Syndromes of the top 6 at 4 and 12 weeks return visit were the same as the first visit. The frecrecies of blood heat syndrome and kidney difficiency syndrome declined, while Qi and Yin deficiency syndrome and blood stasis syndrome increased. At 12 weeks return visit,2 and 3 patterns increased, while 4 and 5 patterns declined.Boosting qi and nourishing yin, coursing the liver, invigorating blood, supplementing the kidney, clearing and draining damp-heat, fortifying spleen and transform dampness, clearing blood heat, clearing dry heat and engendering fluids, supporting heart to calm the nerves were the nine common therapies used by Professor Fan.At the first rank of disease location was "stomach", followed by "liver", then the "lung", "kidney", "heart"Conclusion Emphasizing characteristic dialectical method and lasting movement dialectical view, advocating preventive treatment of disease, skillful usage of Yaochuan, flexible application of medication, are important clinical experience of Professor Fan. The dynamic and fixed sequential program of the diagnosis and treatment, which is appoached by Professor Fan, combined with diet and exercise therapy is a safe and effective prevention program for diabetes patients.
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