Diagnostic Value Of Vascularity Index And Renal Volume With Three Dimensional Ultrasound In Chronic Kidney Disease

ObjectivesTo explore the diagnostic value of the three-dimensional ultrasound parameters-vascularity index(VI) and the volume of kidney in Chronic Kidney Disease(CKD), and assess the degree of renal damage.Materials and Methods125 were studies,95 patients with CKD at different stages and 30 healthy adults served as control, were enrolled in the study. VI and the renal volume were calculated with three-dimensional ultrasound, Resistance index (RI),Cortical thickness(CT) and the volume of kidney were calculated with two-dimensional ultrasound, and the correlation of those parameters were analyzed, Sixty patients is underwent percutaneous biopsy, pathological change scoring of renal were measured, and the correlation of VI and pathological findings as well as clasification of CKD were analyzed.ResultsVI of CKD2 patients reduced significantly compared with the control group, and RI of CKD3 patients increased significantly, Cortical thickness of CKD3 patients reduced significantly, the diagnostic sensitivity, specificity and diagnostic value of VI in patients with early and late chronic kidney disease is higher than the RI; Compared with the control group, three dimension ultrasound of renal volume and two dimension ultrasound volume of CKD1 patients increased significantly, three dimension ultrasound volume of CKD2 patients reduced significantly, and two dimension ultrasound volume of CKD4 patients reduced significantly; Different types of renal diseases had different quantity ofⅥ; Thirty-three patients in the groupⅠ, the diseases limited to the glomeruli,Ⅵwere closed to those of the control group (P>0.05), Twenty-eight patients in groupⅡ, the diseases positioned in the tubulointerstitial and blood vessel,Ⅵwere higher than those of groupⅠand the control group(P＜0.05); There was a significant negative correlation betweenⅥor three dimension ultrasound volume or Cortical thickness or two dimension ultrasound volume and pathological change scoring(r=-0.62 or r=-0.52 or r=-0.43 or r=-0.52); There was a significant correlation between the value ofⅥand the classification of CKD.Conclusions1.Ⅵand three dimension ultrasound volume can detect renal function damage earlier and more sensitive than RI and two dimension ultrasound volume; The lower the VI, the higher the classification of CKD.2.Ⅵcan can reflect the types of renal diseases; In case of CKD withⅥin normal limit, the diseases may be limited to the glomeruli; while theⅥelevated, the diseases may locate in the tubulointerstitial or blood vessel.