| ObjectTo analyze the clinical characteristics of postmenopausal ovarian tumors.Material and MethodsBetween March 2002 and March 2010,416 patients with ovarian tumor (range 43-83, mean age:60.93±6.66, years since menopause (YSM) range:1-43, mean age: 12.01±7.51) operated in Provincial Hospital affiliated to Shandong University. All the patients were naturally menopausal. The diagnosis were confirmed by operation and pathologic analysis. The disease was classified according to the'2003 WHO histological classification of ovarian tumor'. Statistical analysis were performed by software SPSS 17.0. Two sample t test was used to compare mean, and X2 test was used in diversity of the mean compariaion, P＜0.05 was considered statistically significant.ResultsGeneral condition of the patientsAmong the 416 postmenopausal patients with ovarian tumor, rural patients is 176 (42.3%,176/416), and urban patients is 240 (57.7%,240/416).226 patients had benign tumors and 190 malignant (including borderline tumors). The ratio of benign and malignant is 1.19:1. The percentages of different histological types are epithelial tumor 65.1%(271/416), sex cord-stromal tumor 16.1%(67/416), germ cell tumor 14.7%(61/416), metastasis tumor 3.61%(15/416), other tumors 0.48%(2/416).Among the 416 postmenopausal patients with ovarian tumor,the percentages of patients of mean age＜50 is 5.28%(22/416), patients of mean age 50-59 is 43.3% (180/416), patients of mean age 60-69 is 34.9%(145/416), patients of mean age≥70 is 16.7%(69/416).The percentage of YSM＜5-year is 25.5%(106/416), YSM 5-14 year is 39.4% (164/416), YSM 15-24 year is 24.8%(103/416), YSM≥25 year is 17%(43/416).The comparison on the rigion of residence of postmenopausal ovarian tumor patientsThere is no significant difference in the rigion of residence of ovarian tumor patients in different age groups.There is a significant difference between YSM 5-14-year-group and YSM≥25-year-group for the residence of ovarian tumor patients, in which rural patients accounts more in YSM 5-14-year-group,51.8%(85/164) and YSM≥25-year-group is major in urban patients, accounting for 76.7%(33/43).The comparison on the nature of distributon of postmenopausal ovarian tumor patientsThere is a significant difference between 50-year-group and≥70-year-group for the nature of ovarian tumor patients, in which malignant tumor accounts more in 50-year-group,50.8%(95/187) and≥70-year-group is major in benign ones,accounting for 70.0%(42/60).There is a significant difference between YSM<5-year-group and YSM≥25-year-group for the nature of ovarian tumor patients, in which malignant tumor accounts more in＜5-year-group,56.6%(60/106) and YSM≥25-year-group is major in benign ones, accounting for 69.8%(30/43).The comparison on the histological classification of distributon of postmenopausal ovarian tumor patientsThere is a significant difference among＜50-year-group and other groups for the histological classification of ovarian tumor patients.＜50-year-group has a lowest incidence in epithelial tumor and sex cord-stromal tumor, accounting for 47.6% (10/21) and 9.5%(2/21) respectively, but has highest incidence in germ cell tumor and metastasis tumor, accounting for 19.0%(4/21) and 23.8%(5/21) respectively. Epithelial tumor showed significantly higer incidence among the people older than 50, and the propotion is not increased with the age, while germ cell tumor and metastasis tumor showed downtrend among the people older than 50, not down with the age.There is no significant difference in the histological classification of all YSM groups.The difference in the specific age and YSM of postmenopausal ovarian tumor patientsThere is no significant difference in the average age between benign and maligant postmenopausal ovarian tumors.There is a significant difference in the average YSM between benign and maligant postmenopausal ovarian tumors. The average YSM of enign tumor is 12.6years, malignant one is 10.8years, the ovarian tumor patients with shorter YSM has a higher probability than that with longer YSM.Conclusion1. The majority of the postmenopausal ovarian tumors are benign tumors. The incidence of malignant ovarian tumor is the highest in 50 to 59-year-group, but showed decreased in≥70-year-group. YSM＜5-year-group has higest incidence of malignant ovarian tumor, while YSM≥25-year-group showed lowest.2. The majority of the postmenopausal ovarian tumors in histiological classification are epithelial tumors. Epithelial tumor showed significantly higer incidence among the people older than 50, while germ cell tumor and metastasis tumor showed downtrend among the people older than 50.3. The ovarian tumor patients with shorter YSM has a higher probability than that with longer YSM.4. Rural patients in YSM≥25-year-group showed significantly reduced comparing to YSM 5-14-year-group, it should be take seriously to the postmenopausal elderly patients in rural areas.5. Postmenopausal women as one of the three groups of women, we should pay attention to the prevention and treatment of ovarian tumors in postmenopausal women.
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