Study Of The Resection Of Intracranial Lesions Under Electrocorticography

Objective: To investigate the incidence of postoperative epilepsy after resection of intracranial lesions (ICL) under electrocorticography (ECoG), and to investigate the correlation factors of postoperative epilepsy after resection of intracranial lesions.Method: A total of 134 cases with intracranial lesions who received the craniotomy with the electrocorticography monitoring were analyzed retrospectively (treatment group). We used the ECoG monitoring before and after the resection of ICL, thermo-coagulating the cortex if there was epilepsy waves after resection,until the epilepsy waves disappeared or decreased. Another 150 data of patients who get the routine surgery without ECoG monitoring were gathered as the control group. The patients were followed-up after surgery to see the incidence of epileptic seizure. Sex, age, the character, location, size, extent of resection of the ICL, and the preoperative epilepsy were evaluated as the might-be affect factors, and these factors were subjected to multivariate logistic regression analysis, andχ2 test was used to analyze the association of the early postoperative epilepsy(EPOE) and late postoperative epilepsy (LPOE).Result: The incidences of early and late postoperative epilepsy are 16.42% and 13.27% separately in the ECoG monitoring group, while 28.67% and 28.57% correspondingly in the control group. The early postoperative epilepsy is associated with the location, the size of the ICL, the preoperative epilepsy and the extent of resection of the ICL. But the sex, age, and the character of the ICL are unrelated. The early postoperative epilepsy is associated with the late postoperative epilepsy.Conclusion: 1.The use of ECoG monitoring in the resection of the ICL can reduce the incidence of postoperative epilepsy significantly. 2. The ICL in the frontal lobe, with history of preoperative epilepsy and incomplete resection of the ICL are the risk factors of the EPOE, and the small size of the ICL results in lower EPOE rate. 3. The early postoperative epilepsy maybe a risk factor of the late postoperative epilepsy.