Carotid Artery Color Doppler Ultrasound And Analysis Of Related Factors With Ischemic Stroke Patients

Objective: To investigate the characteristics,plaque nature,extent and distribution of vascular stenosis of extracranial carotid atherosclerosis in ischemic cerebrovascular disease of patients, providing an objective evidence to prevent the occurrence of carotid artery ischemic stroke.Methods: cerebral infarction and transient ischemic attack (TIA) patients of the internal carotid artery system with 121 cases and 40 healthy persons Collected from October 2007 to December 2008 was hospitalized in our hospital, were divided into three groups: cerebral infarction group, TIA group and the healthy control group. cerebral infarction patients have71 cases , 53 male, 18 women , aged 46-86 years old, on average (68±12) years old; TIA patients have 50 cases, 30 male, 20 women,aged 45-81 years old, averaged (66±13) years of old; healthy control group have 40 cases,23 cases male, 17 cases women,aged 57-76 years old, on average (65±7) years old. Mainly through the dual function of color Doppler ultrasound detection of extracranial neck vessels, testing the extent of atherosclerosis, intima-media thickness and plaque distribution, and in the light of its history, CT or MRA examination and biochemical analysisResults: 71 cases of cerebral infarction in patients with plaques of extracranial carotid artery plaque were found in 60 cases, of which 32 cases were vulnerable plaque (45.1%), stable plaque were 28 cases (39.4%). 50 cases of TIA patients who were found 36 cases of plaque, including vulnerable plaque in 11 cases (22.0%), stable plaque were 25 cases (50%). Healthy control group who were found in 18 cases of plaque, vulnerable plaque has not been detected, stable plaque in 18 cases. Cerebral infarction group, TIA group of vulnerable plaque between the two groups and the control group were 40 cases of vulnerable plaque, compared to those who have a significant difference (P<0.05), and IMT≥1.5mm when the risk of cerebral infarction higher compared with the TIA group difference was significant (P<0.05), the two groups compared with the control group were statistically significant differences (P<0.05),the parts of plaque occurred with no significant correlation. the lumen in the moderate and severe stenosis of the cerebral infarction and TIA group occurred in patients with higher risk of ischemic cerebrovascular of death, and between the two groups compared with the control group difference was significant (P<0.05). Risk factors: hypertension, diabetes, coronary heart disease, smoking, alcohol consumption, blood lipids, and between the two groups compared with the control group difference was significant (P<0.05), C-reactive protein in the cerebral infarction group and control group with a statistically significant difference (P<0.05), and homocysteine (Homocysteine;Hcy) and other risk factors compared with the control group no significant correlation.(P>0.05)Conclusion: Carotid artery color Doppler ultrasound in the detection of carotid atherosclerosis has important clinical value, some patients with the same period basically the same as in line to check the results of CTA or MRA.It can be in patients with ischemic stroke as the primary means of clinical examination. Ischemic stroke and the severity of carotid atherosclerosis is closely related, and when the carotid artery of moderate and severe stenosis and IMT≥1.5mm when a higher risk of cerebral infarction. CRP is closely related with cerebral infarction, ischemic stroke and Hcy no significant correlation.