Clinical Analysis Of 307 Young Adult Stroke

Objective:To explore the characters of stroke in young adults, to investigate the etiologies and risk factors,understand the prognosis and cause of death of the youth stroke,provided primary prevention for young high-risk groups and the basis for stroke recurrence.Methods: Retrospectively 307 cases of young patients in our hospital with stroke from 2006 to 2008, including 182 cases with ischemic stroke , and 125 cases with hemorrhagic stroke. 1118 cases of more than 60-year-old age patients with stroke were selected as a control group, retrospective analysis the clinical data of cases and the control group. Statistical analysis was assessed by SPSS13.0 statistical packages, single factor analysis byχ~2 test, the Logistic multivariate regression analysis model was used to deter- mine the factors that might significantly influence the incidence of stoke in young adults.Result:1.The youth stroke accounted 9.3% of all patients admitted for stroke.ischemic stroke accounted for 59.3%, hemorrhagic stroke accounted for 40.7%, the proportion of men obvious higher than women, men accounted 74.9%. women accounted 25.1%, the ratio of man to woman is about 3:1.2. The major etiologies of young adult stroke were :early-onset atherosclerosis, cerebral vascular malformation, aneurysm, thromboembolic vascular disease, blood system diseases.The major risk factors were : hypertension, lipid metabolic disorder, smoking, alcoholism, diabetes, history of cardiovascular or cerebrovascular diseases, homocysteic acid, obesity, hypertension and stroke family history, antiphospholipid antibody syndrome,and so on.The etiologeies and risk fators of young and old had significant differences. The young patients often cause a variety of risk factors and etiologies,if the different risk factors occur together in one patient,the effect is not a single stack of the factors, but was duplicated as geometric multiples,the incidence of youth will increase significantly.3.Compared with elderly patients , the proportions of in-hospital case fatality of youth group is significantly lower. The in-hospital case fatality rate of young cerebrovascular disease was 7.2%. The major cause of death: cerebral hernia, central respiratory and circulatory failure and multiple organ failure and infection.4.The cure rate of young patients with stroke is 58.6%,the improve- ment rate is 34.2%,the two datas are higher than old group,the complications are fewer , the course is relatively shorter, crippling rate is lower.Conclusions: 1.The majortiy of stroke in young adults are ischemic stroke and chiefly in male patients.2. The etiologies and the risk factors in stroke of young aldut are diversiform and complex. If the different risk factors occur together in one patient,the incidence of youth will increase significantly.3. The in-hospital case-fatality rate of young's stroke is lower than old group. The prognosis of stroke in young adults are better than olders, the complications are fewer , the course is relatively shorter, crippling rate is lower.4. the primary prevention of stroke in young is the most important.