A Clinical Analysis Of Synthetic Therapy Effect And Prognosis In 107 Patients With Breast Cancer

Objective To investigate the synthetic therapy effect and prognostic factors in 107 patients with breast cancer and explore the relationship between some clinical-pathological factors and prognosis.Methods The analysis of clinical-pathological materials was performed in 107 breast cancer cases who had synthetic therapy,including radiotherapy,surgery,chemotherapy and endocrine therapy .The correlation of age,menopausal status, tumor size,axillary lymph node involvement,TNM stage,hormone receptor status,treatment method with prognosis of breast cancer was evaluated.Result Between 2000 and 2008, 107 patients with breast cancer in total who fit the eligibility criteria were identified and included in the analysis.The 5-year overall survival and recurrence-free survival of the whole patients were 78.5% and 63.6%,respectively. Analysis revealed that 5-year overall survival of this group was significantly associated with tumor size,axillary lymph node involvement,TNM stage and endocrine therapy(P-values﹤0.05).Patient's age,hormone receptor status,menopause status had no significant independent prognostic value ( P -values﹥0.05).Conclusion Our data demonstrate that tumor size,axillary lymph node involvement,TNM stage and endocrine therapy are significant independent indicators of prognosis in breast cancer respectively,and age, hormone receptor and menopausal status are not significant factors of prognosis.