To Study The Functional Regions Of Hand-jueyin Pericardium Meridian In Brain By The Resting-state Functional Magnetic Resonance Imaging

Objective: To research and presume the specific transactivation domains in brain by needling the acupoints of hand-jueyin pericardium meridian with the resting-state functional magnetic resonance image (fMRI), and further explore the function of hand-jueyin pericardium meridian.Methods: 10 healthy subjects were carried out in this trial. The scanning processing involves the resting-state 1(R1), the acupoint stimulating (AP) and the resting-state 2 (R2). Images and datas gained in the workstation was analyzed by these softwares, such as MRI2.0, FSL, AFNI and so on.Results: (1) The activated regions, coming from 10 healthy subjects, analyzed by one-sample t-test during R1 were superior frontal gyrus on both side, the medial frontal gyrus on both side, the left precuneus, the right uperior temporal gyrus, the right declive, the right culme, the right cerebellar tonsil and the left uvula. (2) After acupuncture the the acupoints of hand-jueyin pericardium meridian on the left side, the activated regions analyzed by one-sample t-test during AP were the superior frontal gyrus on both sides, the left middle frontal gyrus, the right cuneus, the left declivis and the semi-lunar lobule. (3) The difference activated regions analyzed by paired t-test between R1 and AP were the cingulate gyrus on both sides, the left lingual gurus, the left declivis, the left cuneus, the right precuneus, the right fusiform gyrus, the right superior frontal gyrus, the right medial frontal gyrus and the right superior temporal gyrus.Conclusions: There are specific transactivation domains in brain by acupuncturing the acupoints of hand-jueyin. The function of these activated regions intimately correlates with the clinic effect of hand-jueyin pericardium meridian.