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Dialectical Liver Failure On The Treatment Of Meta-analysis Of Efficacy

Posted on:2010-07-25Degree:MasterType:Thesis
Country:ChinaCandidate:Y Y MaFull Text:PDF
GTID:2144360275978946Subject:Chinese medical science
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Objective liver failure is caused by many factors of severe liver damage,leading to its synthesis,detoxification,excretion and biotransformation functions of serious obstacles or decompensation appeared to clotting mechanism obstacles and jaundice,hepatic encephalopathy,ascites,such as major the performance of a group of clinical syndrome.In China caused a major cause of liver failure is the hepatitis B virus,followed by drugs,alcohol or chemical toxicant-induced liver damage.Wilson disease,autoimmune hepatitis,acute fatty liver of pregnancy,also can lead to liver failure,there are some liver failure of unknown etiology. Alcohol-induced liver damage due to cirrhosis caused by chronic liver failure,but some patients may be due to alcohol-induced hepatitis and acute or subacute signs of liver failure.In China, the true acute,sub-acute liver failure is relatively rare,and in HBV-related chronic liver disease based on the occurrence of acute (or subacute) the most common liver failure.Hepatic failure complicated illness,prognosis dangerous,high mortality.Chinese medicine theory is not devoted to liver failure.But with "jaundice", "Blood","dropsical bulging," "coma" and other diseases related to Chinese medicine.It is mainly the cause of evil exopathic humid, and the righteousness deficiency related to internal factors. Hygrothermal drug-sheng,diffuse Sanjiao,violations of the spleen and stomach,liver and gallbladder injury.Caused by biliary excretion not Road,impregnated in the skin and yellow,which is traditional Chinese medicine "radical Huang…Pyricularia yellow" areas.And because of its contagious and known as the "yellow plague","yellow-day trip." Hemorrhage,ascites,delirium,then with the "blood evidence","dropsical bulging," "coma" and other related diseases.The main pathogenesis for drug hot flourishing. Reduqing invagination.Wet muddy deceived,obstructing blood stagnation of qi.Documents show that TCM treatment for liver failure to obtain better treatment efficacy.If the basis of huoxuehuayu reuse Chishao,paeonol Liangxue Huoxue drugs,such as the treatment of severe jaundice.Rhubarb preparation guide Tongfu turbidimetry,detoxification,changes in intestinal pH to.At the same time,more than the application of blood,such as carbon adsorption,dampness,and assist the operation of traditional Chinese medicine used to restore the role of intestinal barrier in order to consolidate,by oral or enema treatment intestinal endotoxemia.Syndromes and proposed a phased treatment,the majority of scholars believe that heavy early liver toxicity mainly thermal flourishing.Evil in the air hours.Qingre Huashi,muddy torrents Tongfu;mid-evil into the business of blood,failed to pay disputeuphold and solid.Attention to drug heat,dampness,blood clearance.Fuzheng attention Yiqi,Yangyin,Onyang to "keep body fluid,Bao Wei Qi";late evil depression are offopening and closing, with off and so save the inverse.The purpose of this paper is the systematic evaluation of Treatment of liver failure patients. Methods domestic 1997-2007 published in TCM treatment of liver failure related papers and conference papers,including computer searches,manual searches and references from the Summary of tracking query information.Computer Retrieval of biomedical literature is the CD-ROM Database(CBM),China Journal Net,VIP万方and the full text of the literature database.Manual search in our hospital library.Extraction of them efficient and mortality data,the application of the international collaborative network of evidence-based medicine provided by statistical software Revman4.2 of the data collected by statistical calculation of the treatment outcome after the death of the odds ratio(OR),the clinical efficiency The odds ratio(OR),95%confidence interval (C1),a clear effect of the study after the same amount of the use of fixed-effect model for combined effect of the volume and heterogeneity of the estimated testing and sensitivity analysis.Results Meta analysis of the results suggest that the treatment group died①edge lower than the control group,OR = 0.39,95%CI 0.27 to 0.57.②efficient clinical treatment group edge higher than the control group,OR = 3.44,95%CI 2.40 4.92.No reversal of the results of sensitivity analysis.
Keywords/Search Tags:liver failure, severe hepatitis, Treatment, effect, Meta Analysis
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