| Objective:To observe the clinical effect of pinpricking fixed acupuncture point and equally taking anticholinesterase agents and Traditional Chinese medicine orally on treating Diabetic destrusor underactivity.Methods:Collecting 40 patients in accordance with inclusion criteria and exclusion criteria mainly expressed difficulty in urination and bladder irritation in varying degrees and the urodynamic diagnosis of bladder detrusor underactivity,age from 48 to 60 years old,with an average of 52.3 years old,3-5 years duration for the primary disease,with an average of 4.2 years. 5-11months for the difficulty in urination with 7.3 months on average.Randomized,double-blind divided into categories A,B and C.Group A(13 cases)(Acupoint Acupuncture+Chinese medicine+ anticholinesterase agents neostigmine bromide);Group B(13 cases)(Chinese medicine+anticholinesterase agents neostigmine bromid);Group C(14 cases)(anticholinesterase agents neostigmine bromid)10 days for one course of treatment,take the observation of bladder residual urine,uroflow rate,take on urodynamic three courses of treatment later.Analysis the data before and after the treatment with the use of T,X~2 test,Radit analysis.The statistical software We made use of was SPSS13.0.Acupoint selection:Baihui,Sanyinjiao,Guanyuan,Pangguangshu,Shenshu,Zhongji;anticholinesterase agents:neostigmine bromide tablets; Chinese medicine:Bu Zhong Yi Qi pill.Results:The relevant standards of retention of urine in the efficacy criteria:the light of"traditional Chinese medicine diagnosis of diseases efficacy standards"(State Administration of Traditional Chinese Medicine promulgated in 1994),combined with the development of B-ultrasound and the maximum uroflow rate.Clinical markedly:treatment within a month to restore self-voiding,accompanied clinical symptoms disappear,B ultrasonic examination showed that the bladder residual urine decreased or(and)the maximum uroflow rate boosted by 60%, within 3 months of follow-up without recurrence; Clinical improvement:the patients can self-voiding easilier,Bultrasonic examination showed that residual urine reduced or(and)the maximum uroflow rate boosted by 30%than before;Clinical invalid:clinical symptoms had no amelioratement, Bultrasonic examination showed that the residual urine has no significant reduction or(and)the maximum uroflow rate boosted less than 30%than before.After 3 courses of treatment,the symptoms of the patients in the three groups were alleviated in varying degrees with no significant adverse events.3 months Follow-up in stable condition.①The clinical markedly rate of A was 23.1%(3/13),B was 15.4%(2/13),C was 0%(0/14).The clinical improvement rate of A was 46.2%(6/13),B was 30.8%(4/13),C was 21.4%(3/14).The clinical invalid rate of A was 30.8%(4/13),B was 53.8%(7/13),C was 78.6%(11/14).Total effective rate of A was 69.2%(9/13),B was 46.2% (6/13),C was 21.4%(3/14),After three groups of three treatment courses,the clinical efficiency,effectiveness,the inefficiency,the differences are of statistics significance(P＜0.05).3 groups of patient's clinical symptoms have recovered in the varying degree,the difference of inter-group comparison had the statistics significance(P＜0.05).Showed that the Treatment of A is better than B and C in improving the clinical symptoms.②Selfcomparison:the treatment of A,B in reducing the bladder residual urine,improving maximum uroflow rate are of significantly statistic difference(P＜0.05),the treatment of C group to reduce the bladder residual urine was of no significant difference(P＞0.05).The difference of A group in boosting the detrusor pressure and reducing the abdominal pressure between the treatment was significant(P＜0.05),but not B and C.③Inter-group comparing:After the treatments,the differences among the groups in decreasing bladder residual urine,boosting the maximum uroflow rate and elevating the shrinking ability are of statistical significance.Showed that the treatment of A is better than B and C,B is better than C.
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