| Objective: Colorectal cancer including the colon cancer and rectal cancer is one of the most common malignant tumors of digestive tract. In recent years, with the development of economic, the improvement of people's living standards and the change of lifestyles and living conditions, the incidence and mortality rates of colorectal cancer are increasing. The purpose of this study was the analysis of colorectal cancer in urban and rural areas, gender, age, tumor location and the relationship of Dukes'stage was; and the relationship between the risk factors and pathological types and the tumor sites of colorectal cancer.Methods:1 Collection of cases: I have tracked and followed-up randomly 348 colorectal cancer patients in the Fourth Hospital of Hebei Medical University from December 2007 to December 2008 who took operations there. I take a questionnaire on their dietary ways, the environment and living habits and genetic factors and so on to make a further study. Make use of the questionnaire which was through the uniform preparation and implementation of pre-survey (Table A and Table B). The patients filled the Table A in detail. The contents of Table A: the general situation, dietary factors, personal habits and living habits, past disease history and family history of tumor, whether or not to take non-steroidal anti-inflammatory drugs. Table B was used to investigate 348 cases of colorectal cancer patients with medical information, including: duration (months), the initial symptom, tumor site, digital rectal examination (rectal tumor under the very fate of the length from the anus), colorectal cancer accounted for the mesocaval circumference, maximum diameter of Colorectal Cancer, Cancer in general, histological type, pathological grade, bowel wall invasion depth, extent of lymph node metastasis, Dukes staging, TNM staging.2 The formation of Excel database: To build Excel database after the collection of information3 Statistics in groups: The patients are divided into urban group and rural group by region, into male and female groups by gender, into old age (≥60 years) group, middle-aged (40 ~ 59 years old) group, youth (<40 years old) group by age. Divided into Aden carcinoma, mutinous Aden carcinoma(including signet-ring cell carcinoma) and other types according to pathological types;Divided into right colon, left colon and rectum according to tumor sites;Divided into stage A, stage B, stage C, stage D according to Dukes'stage;Divided into a small number of groups and the regular consumption group according to the amount and frequency of daily food intake, into non-smoking groups and smoking group according to whether or not smoking, into a small amount of alcohol and alcohol group according to whether or not drinking. This study used methods of descriptive epidemiological studies, investigated the characteristics of the population in patients with colorectal cancer, urban and rural distributions, and clinical risk factors and so on, and analyzed the features of distribution of the patients with colorectal cancer. This data are two or more pose than the comparision sample. I have used the statistical package SPSS13.0×list informationχ2 test and it has statistical significance when P<0.05.Results:1 The regional distributionThe difference was significant among the patients of rural group and urban group(P<0.05). The number of patients of rural group was larger than that of urban group; The patients of urban group in stage A and B of Dukes make a larger proportion of the total number of patients than that of rural group; The patients of rural group in stage C and D of Dukes make a larger proportion of the total number of patients than that of urban group.2 Gender DifferencesThere was no statistical significance on the Dukes stage constitute of the patients of Male group and female group.3 Characteristics of groupsThere were statistical significances on the Dukes stages constitute of the patients of Old age (≥60 years) group, middle-aged (40 ~ 59 years old) group and youth (<40 years old) group(P<0.05). The patients of youth group in stage A of Dukes make a higher percentage than that of middle-aged group and Old age group; The proportion of older patients in stage B is higher than that of youth group and middle-aged group; There were more patients of middle-aged group in stage C; Youth group and middle-aged group made a higher proportion of the patients in stage D than older group.4 The position of tumorThere were statistical significances on the differences among the patients of Colon cancer group and colorectal cancer on the Dukes stages'constitute(P<0.05). The proportion of patients in stage A of colorectal cancer was significantly higher than that of colon cancer; the number of colon cancer patients in stage D is larger than that of colorectal cancer patients; and there was no statistical significance on the differences among the two groups of patients with stage B and stage C,χ2 =1.872,P=0.171>0.05.5 Eating habits5.1 There were statistically significant differences (P<0.05) between the amount of consumption of fresh vegetables (g / d) and the composition of the tumor, the number of the patients of a small amount group with left colon cancer was significantly larger than that of regular amount group; The number of the patients of regular amount group with rectal cancer was smaller than that of a small amount group; There was no statistical difference between the amount of the consumption (g / d) of fresh fruit and the composition of tumor sites, the amount of the consumption of fresh vegetables and fruit (g / d) and the constitutes of the pathologic type of colorectal cancer.5.2 There was no statistical difference between the amount of consumption of eggs (g / d), milk (g / d), poultry (g / m) and fish (g / m) and the pathological types of colorectal cancer and the composition of the tumor sites.5.3 The patients were divided into a small amount of consumpti- on group and regular consumption group by average weekly eating times of park and beef. There were statistically significant differences(P<0.05) between the two groups of patients and the different compositions of the pathological types of colorectal cancer. The number of the patients of regular amount group with mucous Aden carcinoma (including signet-ring cell carcinoma) was larger than that of a small amount group; The number of the patients of a small amount group with other pathological types was larger than that of regular amount group; There was no statistically significant difference between the two groups of patients and the composition of the tumor sites.5.4 The patients were divided into a small amount of consumpti- on group and regular consumption group by average monthly eating times of processed meat (times / month). There were statistically significances between the two groups of patients and the pathological types and the composition of the tumor sites of colorectal cancer(P<0.05). The number of the patients of regular amount group with mucous Aden carcinoma (including signet-ring cell carcinoma) and other pathological types was significantly larger than that of a small amount group; the number of the patients of a small amount group with Aden carcinoma was larger then that of regular amount group; the number of the patients of regular amount group with right colon was larger than that of a small amount group; the number of the patients of a small amount group with colorectal cancer was larger than that of regular amount group.6 There was no statistical difference between whether or not heavy drinking and smoking and the pathological types of colorectal cancer and the composition of tumor sites.Conclusion:①The patients in the City of Shi Jiazhuang in the early stage (stage A and B) of Dukes make a larger proportion of the total number of patients than that of rural group;the patients of rural group in the late stage (stage C and D) of Dukes make a larger proportion of the total number of patients than that of urban group.②Youth group and middle-aged group made a higher proportion of the patients in stage D than older group.③Early diagnosis of rectal cancer patients was higher than that of patients with colon cancer.④Low intake of fresh vegetables was possible risk factors for left colon cancer.⑤Regular eating of park beef and processed meat products may increase the risk of getting higher-grade mucous Aden carcinoma; Regular eating of processed meat products may increase the possibility of getting right colon cancer.
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