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The Clinical Research On Tiaozhi Hugan Decoction For Fatty Liver

Posted on:2010-05-28Degree:MasterType:Thesis
Country:ChinaCandidate:Z Y ChenFull Text:PDF
GTID:2144360275960059Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Fatty liver is caused by a variety of reasons,especially the liver lipid over-accumulation of triglycerides,when lipid accumulation in liver cells of more than 5%of liver wet weight or per unit area of study 1/3 of the liver cells become fat when it is called fatty liver.With the improvement of living standards and changes in diet,the incidence of fatty liver showed an upward trend year after year.The past that only benign fatty liver,but in recent years found that 20%of cryptogenic cirrhosis may be fatty.Development of hepatitis.Chinese medicine treatment in order to clear the advantages of fatty liver,we carried out the treatment of Tiaozhi Hugan soup clinical study of fatty liver.Objective:Essentiale and western medicine and the comparative control,a clear soup Hugan Tiaozhi fatty liver in the treatment of genuine good effect.Methods:The reference to"Chinese medicine clinical research guiding principles"for the diagnosis of fatty liver patients,the use of random allocation will be divided into traditional Chinese medicine study Tiaozhi Hugan group Essentiale western medicine group and blank control group,a total of 90 cases.Application of this study were self-made Tiaozhi Hugan soup, western medicine Essentiale and blank cont fefrol(without any drug)treatment, treatment for 8 weeks,treatment effects of not taking any other drug test results,treatment before and after blood Detection of the above indicators of lipid and liver function,and compare its image before and after treatment (B super)changes.Results:①The lipid regulating effects:comparison before and after treatment groups:experimental group and control group of western medicine can reduce TC,TG,increased HDL-C(P<0.01,P<0.01).The end of the treatment group comparison:treatment of patients with the end of TC,TG experimental group was significantly lower than that of western medicine control group(P<0.05),and HDL-C increased significantly(P<0.05),showed that patients with fatty liver in the regulation of blood lipids efficacy of Chinese medicine is better than soup Tiaozhi Hugan Essentiale western medicine.②to improve the impact of liver function:comparison before and after treatment groups: experimental group and control group of western medicine can be reduced AST, ALT,ALP and GGT(P<0.01).The end of the treatment group comparison:patients with AST,ALT,ALP and GGT was significantly lower than western medicine,the experimental group the control group(P<0.05),showed that patients with fatty liver in improving the efficacy of liver function,Chinese medicine is better than soup Tiaozhi Hugan western medicine Essentiale.③of imaging(B Ultra) the impact of:before and after the treatment group compared:the experimental group and control group of western medicine imaging after treatment showed fatty infiltration of liver cells was significantly lower than before treatment,the difference was statistically significant(P<0.01).After the treatment group compared:the experimental group showed its imaging fatty infiltration of liver cells in the control group is lower than western medicine, the difference was statistically significant(P<0.05).④to improve the impact of clinical symptoms:comparison before and after treatment groups: experimental group and control group after treatment of western mefefdicine TCM Syndrome points than before treatment has declined,the differences are statistically significant(P<0.01,P<0.01),comparing treatment groups: the experimental group and control group of western medicine TCM Syndrome points statistically significant difference(P<0.01),that is,Chinese soup Tiaozhi Hugan points in traditional Chinese medicine syndromes of Western medicine is superior to the lower Essentiale rehabilitation.⑤The total effective rate of comparison:the treatment of fatty liver in the experimental group there are always more efficient than western medicine,the control group, the difference was statistically significant(P<0.05).CONCLUSION:①Decoction of Chinese medicine and western medicine Hugan Tiaozhi Essentiale for different degrees of fatty liver patients have significant reduction of clinical symptoms,regulating blood lipids(TC,TG and HDL-C)levels,improve liver function(AST,ALT,ALP and GGT)damage, reduce fatty infiltration of liver cell cancer.②Compared with Western medicine Essentiale compared Hugan Tiaozhi Tang in Chinese medicine to alleviate clinical symptoms,regulating blood fat levels,improve liver function damage,reduce fatty infiltration of liver cells and so on are better than western medicine Essentiale.③Chinese medicine and western medicine soup Hugan Tiaozhi Essentiale clinical observation in the whole none of the serious adverse reactions and toxicity,safety.
Keywords/Search Tags:fatty liver, soup Hugan Tiaozhi, Essentiale, clinical efficacy
PDF Full Text Request
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