The Expression Of Tissue Factor In Renal Cell Carcinoma And Its Clicinal Significance

Objective To inspect the expression of tissue factor (TF) in renal cell carcinoma and in adjacent normal renal tissues ,and to know the relationship of tissue factor expression with carcinogenesis and progression in renal cell carcinoma and its clinical applying value in renal cell carcinoma treatment.Methods Detected the expression of tissue factor in 30 cases of renal cell carcinoma and 15 cases of the adjacent normal kidney tissue by MaxVision? immunhistochemistry method,then analyzed the results by comparing its.Results The expression rate of tissue factor in renal cell carcinoma is 90%(27 cases are positive in 30 cases of renal cell carcinoma )was significantly higher than in the adjacent normal kidney tissue of 13.3%(2 cases are positive in 15 cases of the adjacent normal kidney tissue). The expression of tissue factor in renal cell carcinoma and the adjacent normal kidney tissue was sinnificantly different and the difference have statistics significance.Conclusion Maybe there is a close relationship between tissue factor and renal cell carcinoma,According to the different of the expression of tissue factor in renal cell carcinoma and the adjacent normal kidney tissue,the tissue factor may be used in diagnose and targeted treatment of renal cell carcinoma. It may be significant in the treatment of renal cell carcinoma.