Clinical Research Of Yiqi Sanju Formula In Treating Metabolic Syndrome And Hyperuricaemia

BackgroundMetabolic syndrome is a metabolic inordinate group,mainly including central obesity,hypertension,insulin resistance and dyslipidemia. Hyperuricaemia is induced by purine turbulence and(or) excrete diminish. At present,hyperuricaemia is not a part of MS,but it has close relationship with MS.Some new researches have found that,hyperuricaemia generally goes with MS,and seriously influences the development and prognosis of MS.MS and hyperuricaemia should be treated and prevented as early as possible,however,modern medicine is short of effectual medicine intervention study.Tradition Chinese medicine has some advantages in early prevention and treatment of MS and hyperuricaemia, but it is short of systematic theoretical guidance.ObjectiveTo observe the therapeutic effects of Yiqi Sanju Formula(YQSJF), a compound Chinese herbal medicine,in treatment of metabolic syndrome (MS)and hyperuricaemia.MethodsThe 32 patients diagnosed were treated with YQSJF for 12 weeks, clinical symptoms,body mass index(BMI),waist circumference, waist-to-hip ratio(WHR),homeostatic model assessment for insulin resistance(HOMA2-IR),serum uric acid,fasting blood glucose,fasting blood insulin,triglyceride(TG),high-density lipoprotein(HDL),urine series albumin were evaluated before and after treatment.ResultsAfter treatment,the levels of BMI,waist circumference,WHR,UA, HOMA2-IR,TG,HDL and urine albumin were decreased significantly(P＜0.01 or P＜0.05).We also found that,BMI,waist circumference has serious influences on serum uric acid.ConclusionYQSJF has a certain extent therapeutic effects on MS and hyperuricaemia.Hyperuricaemia has a strong relationship with MS.