| Objective:To observe the brain edema change of 59 patients with spontaneous intracerebral hemorrhage by combined treatments 6 traditional Chinese medicine and western medicine and timely clinical observe dynamic state of brain edema with noninvasive BORN-BE monitor.Method:59 clinical SICH patients were randomly divided into two groups.The experimental group of 30 patient swere given Huang Jiao grain and mannitol consociation treatment;the latter 29 patients were adopted mannitol dehydrate treatment alone.59 patients of these two groups are also accepted general normal regulations treatment processing.The non-invasive BORN-BE monitor were used to mersured the comprehensive agitating coefficient of two Cerebral hemisphere at 1,3,5,Rdays later after onset and the change of cephalophyma size was measured and calculated bythe duo tian shi formula and low density voluminal size of cephalophyma periphery at 1,4,Rdays later after onset Chinese medicine syndrome integral was appraisaed by the Chinese medicine diagnostic method, neurologic impairment(NIHSS) integral was appraisal by the neurologic examination. Results:(1).At the 1st day of onset,whether the experimental group or the control group,The comprehensive agitating coefficient in focus side was lower than the unaffected side in both groups(p＜0.01).As the disease progressed,however,the comprehensive agitating coefficient was very obviously different,the coefficient in the focus side was higher than the unaffected side in the third day in the two groups(p＜0.01);The coefficient in the focus side was also higher than the unaffected side in the 5th day in the two groups,but difference growed down(p＜0.01);The coefficient in the focus side was also higher than the unaffected side in the 8th day in the two groups,but difference became approximately equal,no statistical significance(p＞0.05). Experimental group compared with the control group,The comprehensive agitating coefficient had no obviously difference in the two groups in the 1st day(p＞0.05),but The comprehensive agitating coefficient has very obviously difference in the two groups in the 3th,5th and 8th day(p＜0.05),coefficient in the experiment group was lower than that in the control group.(2).At the first incidence of one day,Chinese medicine syndrome and neurologic impairment(NIHSS) integral was no statistical difference in the two groups(p＞0.05);But in the 4th and 8th day of the treatment,two the integral contained difference,particularly,the difference was significant at the 8th day,Chinese medicine syndrome and neurologic impairment (NIHSS) integral in the experiment group wereboth lower than that in the control group,and the difference had statistical significance(p＜0.01). (3).The comparison of the capacity change of cephalopyma and low density voluminal of cephalophymaperiphery had no statistical significance in the two groups on the 1st day by the measuring of imageology based on the assessment formula(p＞0.05).But on the 8th day of the course,the capacity of low density.voluminal of cephalophyma periphery aggrandize obviously each group than that in the 1st day.The comparison of the capacity change of cephalophyma and low density voluminal of cephalophyma periphery had statistical significance both group,and it was less in the experiment group than in the control group(p＜0.05)。Conclusion(1).curative effect of combined traditional Chinese medicine and western medicine was superior to pure Western medicine in the spontaneous intracerebral hemorrhage patient; The difference of two groups with the brain edema, cephalophyma,or Chinese medicine syndrome integral and neurologic impairment(NIHSS) integral had statistical meaning.The effect of experimental groups were significantly better than that of the control group.(2).The non-invasive brain edema monitor was sensitive,objective and practical to reflect the changes of cerebral edema in ICH patients.BORN-BE cerebral edema non-invasive dynamic monitoring of BE in the clinical monitoring was accurate,sensitiveand practical,monitor was non - invasive and could be used dynamic and timely monitoring,which could provid a clear objective data on the clinical diagnosis and medication,avoiding blind medication.Non- invasive cerebral edema dynamic monitor could be a useful supplement as CT,MRI,and it could be widely used in primary hospital,and it had practical guide significance.
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