The Impact Serum Plevel And E2/P Level Of HCG Administration On Outcomes Of In Vitro Fertilization-embryo Transfer

Objective:To evaluate the impact of progesterone(P) level and E2/P level of HCG administration on outcomes of in vitro fertilization in controlled o varian hyperstimulation.Method(s):658 cycles of IVF/ICSI performed in our reproduction center fro m N-ovember 2006 to November 2008 were analyzed retrospectively.The se cycles were stratified according to P levels of≥1.04ng/ml or＜1.04ng/ml and according to E2/P levels of≥1.51 or＜1.51.This cutoff level was selected because its yielded the highest sensitivity and specificity according to a receiver operator characteristic curve.Result(s):In cycles with high serum p levels,less oocytes were retrieved,clinical pregnancy rate was33.8%(in cycles with low serum P level were 44.6%),respectively(P＜0.05).In cycles with high serum E2/p levels,more oocytes were retrieved and the cleavage rate was high. respectively(P＜0.05).Conclusion(s):Our data showed adverse effect of high serum P levels on the day of HCG administration on clinical pregnancy rate.The level E2/P can anticipation the numbers of oocytes,the cleavage rate,high-quality embryo rate et al.