The Clinical Research Of Adjuvant Therapy Of Syndrome Differentiation And Treatment Of Traditional Chinese Medicine (TCM) On AS

ObjectiveThis study based on the clinical findings that most ankylosing spondylitis (AS) patients were young and middle-aged, combined with the author mentor's many years of research experiences of the disease, thought the key to the pathogenesis of ankylosing spondylitis were the "essence infirmity and appearance eusthenia, tendon and vessel lose support, humid heat hinder tendon and vessel ", thus used" eliminating humid heat, invigorating the kidney and blood, keeping tendon and vessel soft and smooth "as the basic treatment of regulation , based on the author mentor's many years of research experiences, on the basis of Siwutang , the dialectical use of the rattan species of Chinese medicine to cure the disease and achieved satisfactory results. This study used a random parallel research methods, through Clinical Observation on adjuvant therapy of Syndrome differentiation and treatment of Traditional Chinese Medicine on AS, and explored the pathogenesis, treatment, prescription drug laws of treatment of Traditional Chinese Medicine on AS, provided a theoretical basic and clinical basic programs for the formulation of Syndrome differentiation and treatment of Traditional Chinese Medicine on ankylosing spondylitis.MethodThis study confirmed the clinical selection for patients with ankylosing spondylitis for prospective randomized controlled trial, according to test group: control group =1:1, a total of 62 cases of patients with a random search through random number tables, should be screened for simple randomization according to the visit time of the patients, and respectively, gave the test group herbal medicine , nimesulide capsules, basic treatment and the control group nimesulide capsules, basic treatment. The tests were carried out in strict requirement, and selected the final total of 62 cases. Both test group and control group patients had no loss.ResultsCompared to the general information of two groups of patients before treatment including the age, gender, disease duration, the main sign, sub-sign, the overall functional classification, the differences were not significant (p> 0.05), the baseline before treatment were basically the same.Compared separately the score before and after treatment in the two groups of patients, the clinical symptoms of test group patients after treatment, such as the overall function, laboratory indicators, etc, had been markedly improved than before, the differences were significant (p <0. 05) ; the clinical symptoms of control group patients after treatment, such as the overall function, laboratory indicators, etc, also had been markedly improved than before, the differences were significant (p <0.05); the sacroiliitis X-ray classification of test group and control group before and after treatment had no obvious changes, there were no significant differences (P> 0.05), but compared the sacroiliitis X-ray classification of the test group after treatment with the control group after treatment there were significant differences(P<0. 05), noted a significant effect of sacroiliitis maintenance and stability in test group compared to control group; but the changes of distance before and after treatment between pulvinar to the wall in the two groups were not significantly improved (p> 0.05).Compared the score improved before and after treatment in two groups of patients, such as the clinical symptoms, the overall function, laboratory indicators, the test group improved much more than the control group, the differences between the two groups were significant (p <0.05), while the pulvinar wall distance, chest expansion, etc. improved the level of no significant differences between the two groups (p> 0.05).ConclusionThe adjuvant treatment of Syndrome differentiation and treatment of Traditional Chinese Medicine on ankylosing spondylitis can significantly improved the patients' mental, behavioral status, activities of daily living as well as the ability to exercise. For those who diagnosed with ankylosing spondylitis, early intervention of treatment of Traditional Chinese Medicine on patients with AS , had achieved a certain degree of clinical efficacy in improving symptoms, slowing disease progression, improving quality of life, which is worthy to be popularized and further studied.