| Objective: To investigate Tongfu Tang on normal rabbit pancreatic exocrine function of further observation Tongfu decoction of acute pancreatitis and pancreatic tissue rabbit serum amylase the impact of acute pancreatitis and to explore the mechanism of oral medicine and feasibility.Methods: Experiment 1: New Zealand rabbit 32, respectively, as the stomach and the jejunum to Tongfu soup (6 ml kg-1) to 1, and then draining pancreatic juice 1 hour, the drainage of the pancreatic juice pancreatic juice in the volume and bicarbonate Ion content and pancreatic protein content.Experiment 2: New Zealand rabbit 40, were randomly divided into sham group, model, Tongfu soup gavage group, Tang jejunum group and Tongfu jejunum food group. All eight. To retrograde cholangiopancreatography pressure injection since the method of bile (0.5 ml / kg) established rabbit model of acute pancreatitis and use of Chinese medicine compound Tongfu soup for early intervention, 4 h after the blood test to serum amylase, killed rabbits, and the pancreas Pathological observation.Results: 1: normal Tongfu-rabbit pancreatic juice can not increase the total circumstances to increase their bicarbonate ions in the relative reduction in pancreatic protein and the stomach and the jejunum administration had no significant difference. The soup can Tongfu experimental acute pancreatitis rabbit serum amylase significant decrease in its pancreatic pathology significantly improved, and the stomach and the jejunum administration had no significant difference.Conclusion: Early oral medicine Tongfu pancreas soup can be rest and to prevent intestinal paralysis, and the increase in bicarbonate ions reduce the secretion of trypsin, improve microcirculation, and promote intestinal peristalsis may be one of its mechanism.
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