Immune Synergies Research Of APS

Polysaccharide(Polysaccharide) for a large class of natural products,are widespread in animals, plants,micro-organisms,such as in.Because of their extensive source of cheap,precise effect of natural,a wide variety of biological activity functions,by the people's universal attention, polysaccharide the development and utilization of biological resources and research increasingly active, a natural medicine,biochemistry.Life science research hot spots.So far,nearly 100 more carbohydrate compounds from natural products were separated.Polysaccharide all biological organisms is not only an important structural elements,but also an important elements of information,participation in molecular recognition cell adhesion and cell defense mechanisms.In recent years,large number of pharmacological and clinical study showed that the polysaccharide compounds is a good immune regulator.It can activate immune receptors,enhancing the body's immune function.Thus,in modern animal husbandry,development and utilization of natural polysaccharide extract as immune regulator, by the people's universal attention,a lot of research.Study on the APS of the extraction,isolation,physical and chemical properties and polysaccharide content.Alcohol use of water-extraction APS.Molish reaction,were used iodine-potassium iodide reaction Ninhydrin-reaction of the APS extracts of the physical and chemical properties.And use of phenol sulfate detected polysaccharide content.Available from the APS in the polysaccharide content of 81.3%.Total sugar content of 81.3%APS conducted toxicity tests and safety evaluation.The results suggest that APS can be used for non-toxic oral,injection and other immune,and non-toxic side effects,safe and reliable.APS on the body have a certain impact on weight gain can increase the body weight. China's foot-and-mouth epidemic is very grim,the state submitted in accordance with foot and mouth disease reference laboratory analysis of samples and found my foot and mouth disease virus serotypes still O-oriented,but in some areas from the disease have type A sample of material And Asial I-detection.Application of vaccine to prevent animal disease prevention is still the main measure.Chinese medicine has broad enhance immune activity.Thus can develop into new Immunostimulants.Therefore,the development of high efficiency,low toxicity of new Immunostimulants have become eager to solve the problem.Study on the Asial I antigen and the emulsification effect of APS,animal vaccination,a different degree of response,after immunization before vena cava blood sampling and testing antibody titers, and duration observation of antibodies,vaccines are the best Proportion dose.Research on the impact of cytokines.APS adjuvant to the vaccine's effect on the release of the body that stimulate the immune cells produce IL-2 effect,making the body's immune cells to anti-virus,anti-bacterial,anti-tumor immunity.With antibody titers and the impact of cytokines,that the 100 ug / ml as the best dose ratio.