The Clinical Study Of Spleen Qingchang Soup On Ulcerative Coliticis

Objective: Ulcerative Coliticis is an inflammatory bowel disease of unknow etiology. The disease course of a long, and often repeated attack, and the incdence of colon cancer and to certain extent ,and thus difficult to cure by the world health organization as one. Western medicine treatment of this disease are easy to relapse after treatment,long-term medication reaction,intractable cases of shortcomings such as poor. So to find effective,less side effects of drugs has become the focus of its research. Treatment of ulcerative colitis with significant advantages in the development of outstanding value and broad prospects.This paper summarized in the medical awareness of the disease, and evaluation of clinical research soup jianpi qingchang the efficacy and mechanism for the treatment of the disease to provide new and effective drugs. Methord: the subjects to Jianpi Qingchang soup for the treatment of drug. Subject to the observation of patients with ycerative colitis object. Topics observed clinical symptoms, signs, as the intestinal muosa colonoscopy, IgG,IgA, IgA,IgM, ESR, CRP and C3. Choice of topics selected with the standard 60 cases of patients.. A randomized, controlled clinical trial of parallel methods. Issue will be in accordance with the principle of the patients were randomly divided into Jianpi Qingchang group (experimental group) and sulfasalazine (control group), each of the 30cases. Spleen test group taking the pral enema Qingchang soup control group given oral sulfasalazine, and 1 g each, three times a day. One month for the two groups to have a course of treatment, continuous observation of the three courses. Result: The test showed that: Spleen Qingchang soup treatment of ulcerative colitis(spleen deficiency damp-heat) clinical cure rate was 76.6%.the total efficiency of 90%.control group, the clinical cure rate 46.67%. the total efficiency of 63.66%percent. When comparing the two, and the total efficiency an clinical cure rates were significantly batter than the control group. Clinical Syndromes study showed that: ulcerative colitis( spleen deficiency damp-heat) of the clinical symptoms after treatment Jianchang soup can effectively be improved if Nongxue it, The number of diarrhoea, abdominal pain, Lijihouchong, abdominal distension, such as anorexia. Colonoscopy results show that: Spleen Qingchang soup before and after the treatment of ulcerative colitis efficient and clinical cure rates were significantly better than control group. Blood testsL spleen Qingchang soup has anti-inflammatory effects, to repair lesions, can protect intestinal mucosa. Ulcerative colitis exist immune dysfunction. Performance of ESR, CRP,IgG,IgA,IgM,C3 abnormal increase, after Jianpi Qingchang soup after treatment,these cytokines basically returned to normal.Conclusion:The combination of modern medicine and traditional Chinese medicine pharmacology research:regulate immune runction,inhibit colonic mucosa damage,and promote ulcer repair,thelocal vascular diseases ulcerative colitis,and other aspects of the role may be the main mechanism to take effect.