Clinical Observation On Bone Wilting Due To Kidney Taxation With The Methods Of Invigorating Spleen And Tonifying Kidney Dissipating Dampness And Resolving Blood Stasis

Objects: Through observing the methods of invigorating spleen> tonifying kidney,dissipating dampness and resolving blood stasis on the change of the relevant laboratory's values and clinical symptom on the patients who are bone wilting due to kidney taxation , we discuss the effect of this methods on bone wilting due to kidney taxation.Methods: we select 60 cases of yang deficiency of spleen and kidney with turbidity stasis stagnancy, and divided them into two groups at random, the therapy group and the control group. On the basic therapy, the control group is given VD3, and the therapy group is given herbal decoction which follows the principle of invigorating spleen,tonifying kidney, resolving dampness and dissipating blood stasis—Gugu decoction. After one period of treatment with three months, we observe the laboratory's values, such as clinical symptom, BUN, Scr, iPTH, P, Ca, CaXP, to compare the two groups before and after therapy.Result : (1)In reducing the accumulating grade of TCM syndrome there was significant difference in both groups before and after theraphy(p<0.05), and between the groups(p<0.05) the therapy group is better than the normal group .(2)On the aspect of improving the renal function, before and after therapy there was significant difference both the two groups (p<0.01 or p<0.05), and between the two groups(p<0.05).(3) On the aspect of improving clinical tests, before and after therapy there were significant difference on PTH, P and the product of P and Ca both the two groups (p<0.05). There was significant difference between the two groups, and the therapy group is better than normal group(p<0.05). There is no significant difference on the P and AKP in serum between the two groups(p>0.05). Conclusions: 1. The methods of invigorating spleen, tonifying kidney, dissipating dampness and resolving blood stasis can treat the syndrome of yang deficiency of spleen and kidney with turbidity stasis stagnancy on CRF, and the symptom can be improved significantly.2. The methods of invigorating spleen,tonifying kidney,dissipating dampness and resolving blood stasis can improve the the abnormal of Ca,P in blood serum, retard the progression of CRF, protect the renal units.3. The methods of invigorating spleen,tonifying kidney,dissipating dampness and resolving blood stasis is better than the normal group on the aspect of improving the clinical symptom and test index. This methods may be a new idea on treating bone wilting due to kidney taxation...