| Objective: To study the MCP-1, MMP-9 in endometriosis (EndometriosisEMs) and its significance in and of the mutual relations between the two, for the development of EMs provide a theoretical basis.Methods: EMs (EMs) specimens, peritoneal fluid, the capsule of the 30 cases as a test group, to collect samples of normal ovarian, peritoneal fluid as the 25 cases, all cases were confirmed by pathology, with cases more than the standard group, by immunohistochemical SP Chemical Detection MCP-1, MMP-9 in EMs organizations, normal ovarian tissue; dual-antibody sandwich ELISA technology (SandwichELISA) Detection of peritoneal fluid, liquid capsule factor in the level of expression of the two EMs and the occurrence and development of the relationship. SPSS13.0 application of statistical software packages for statistical analysis.Results: 1. MCP-1, MMP-9 expression was as follows: MCP-1, MMP-9 in EMs of expression were significantly higher than that, the differences were statistically significant (P = 0.032, P = 0.048).2.MCP-1, MMP-9 in different clinical stages EMs in the expression: MCP-1 in EMs Group III, IV of tissues than I,â…¡period, the differences were significant (P = 0.008 ). MMP-9 in EMs Group III, IV of ovarian tissue also higher than I,â…¡period, there are significant differences (P = 0.014).3. MCP-1, MMP-9 in the peritoneal fluid level are as follows: EMs group compared with the control group, MCP-1, MMP-9 levels are significantly increased, the differences were statistically significant (P = 0.000, P = 0.000).4. MCP-1 in the peritoneal fluid EMs Group, in the capsule of the level are as follows: in the capsule of the MCP-1 levels were significantly higher than the peritoneal fluid, had a significant difference (P = 0.000). MCP-1 in EMs Group III, IV of peritoneal fluid, the capsule of water in an average of more than I,â…¡period, the differences were statistically significant (P = 0.002, P == 0.000).5. MMP-9 in EMs Group peritoneal fluid, cystic fluid level in the following: in the capsule of the MMP-9 levels were significantly increased in the peritoneal fluid, had a significant difference (P = 0.000). MMP-9 in EMs Group III, IV of peritoneal fluid, the capsule of water in an average of more than I,â…¡period, the differences were statistically significant (P = 0.000, P == 0.037).6. MCP-1 and MMP-9 expression of the following: in MCP-1 and MMP-9 expression correlation: MCP-1 and MMP-9 with the expression of consistency, (P = 0.559); EMs Group peritoneal fluid In the MCP-1 and MMP-9 level of expression: MCP-1 and MMP-9 are related to the expression, (P = 0.028); EMs group in the capsule of MCP-1 and MMP-9 level of expression: MCP - 1 and MMP-9 are related to the expression (P = 0.001).Conclusion: 1.MCP-1 protein in EMs of expression increased significantly, MCP-1 protein expression and EMs may increase the incidence of development, and clinical stage of the EMs with the increase and increased expression, but the cause is EMs Or the results of the present, surviving in the current dispute.2. MMP-9 in EMs of expression increased significantly, MMP-9 protein expression and EMs may increase the incidence of development, and clinical stage of the EMs with the increase and increased expression, suggesting that MMP-9 is likely to lead to progress in EMs An important protein.3. MCP-1 and MMP-9 in the peritoneal fluid and the fluid in the sac expression, suggesting that the change in the environment within the abdominal cavity in the pathogenesis of EMs may play an important role, and with the clinical stage of the EMs and increase the level of increase, EMs may be used as a clinical reference.4. EMs organizations. MCP-1 and MMP-9 expression was significantly higher at the same time, and has a consistency, MCP-1 and MMP-9 in the peritoneal fluid and the fluid in the sac in positive correlation between the multiple factors that prompted EMs Interaction between the results, MCP-1 and MMP-9 in EMs in the pathogenesis of the possible synergies.
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