The Association Of QT Dispersion And Coronary Artery Disease

ObjectiveTo explore the relationship between the severity and extent of coronary artery stenosis and QT dispersion (QTd) and corrected QT dispersion (QTdc) ,and To explore the effect of percutaneous coronary intervention (PCI) on QT dispersion (QTd) and corrected QT dispersion (QTdc) in patients with coronary heart disease.Methodseighty-three patients underwent conorary angiography (CAG) .according to the severity of coronary artery stenosis, fifteen patients with coronary artery stenosis ranging from 50% to 70% were enrolled in the moderate stenosis group. forty-six patients whose stenosis>70% were enrolled in the severe stenosis group, according to the exent of coronary artery stenosis, Thirty patients with ene-vessel stenosis were enrolled in the one-vessel stenosis group. Thity-one patients were enrolled in the over two-vessel group. Twenty-two patients who were proved not to be CAD with stenosis < 50% by conorary angiography were enrolled in the control group, Include coronary microvascular diseases. Measure the QT dispersion of ECG for all patients the first time after admission, and the QT dispersion for the severe group after PCI. Compare the QTd and QTdc of each group ,and for the pre-PCI and after PCI of the severe group.ResultsThe effectiveness on QTd and QTdc was not significant in the severe and moderate stenosis group (P>0.005) , The effectiveness on QTd and QTdc was also not significant in the over two-vessel group and one-vessel stenosis group (P > 0.05) . QTd and QTdc were decreased significantly in treatment group after successful PCI (P (0. 05) .ConclusionThe severity and stenosis of coronary artery had a not clear relation with QTd and QTdc, More severe the myocardium ischemia and injury were, not necessarily more obvious the QTd and QTdc extension will be. Sucessful PCI could decrease QTd and QTdc significantly and reduce the repolarization dispersion.