| Objective:To analyse uric acid concentration and clinical feature of coronary heart disease patients which were diagnosed definitely. To study the prevalence of hyperuricemia of CHD patients,and explore the relationship between hyperuricemia and gender,age,CHD,diabetes, dyslipidaemia,CR,to guide prevent and treat patients of CHD with hyperuricemia.Methods:A total of 132 patients who were admission in ZheJiang University Medical collage affiliated 2ndhospital from Jan.2005 to Oct.2007,according to uric acid concentration,normal uric acid group and hyperuricemia group is determined,measure and register age, symptom,sign etc,uric acid concentration,FBG,cholesterol,and the result of echocardiography,coronary angiography were recorded.All statistical analyses were using SPSS 15.0 for Windows.Quantitative data were expressed as mean±SD,if they were normally distributed. Correlations were assessed using logistic regression method or partial correlation whenever appropriate.Data between groups were assessed using independent-samples T test and x2 test.P values were two-sided and that less than 0.05 was considered significant.Results:There was no significantly difference between age,compared to normal uric acid group, hyperuricemia group has higher BMI,FBG,TG,LDL-c,male patients have higher uric acid concentration,coronary angiography shows that there was much more diffuse and multi-vessel lesions in hyperuricemia. Logistic regression analysis showed that UA was a risk factor of CHD, obesity,FBG,BMI,TG,LDL-c are also important risk factor. Conclusions:In CHD patients,there is more severe lesions with hyperuricemia,and more MS,UA is an important factor to occurrence and development of CHD and is of clinical significance to control UA.
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