The Study Of The Chemotherapy And Chinese Product YMHJYGJ's Influences To The H22 Hepatocellar Carcinoma-bearing Mice

Objective:To observe the inhibition of the chemotherapy and Chinese product YMHJYGJ to the H22 hepatocellar carcinoma-bearing mice.Method:kunming mice 60, Divides into Control group,Western medicine grop,Cooperation of Chinese and Western medicine grop,Chinese drug grop Stochastic ally, Each group of 15, Uses the H22 hepatocellar carcinoma-bearing mice animal model, Gives the control group physiological saline to fill separately feeds, The Chinese native medicine YMHJYGJ to fry fills feeds, Western medicine 5- fluorine intraperitoneal injection, As well as the product YIMIHUAJIYIGANJIAN to fry fills the stomach and 5- fluorine intraperitoneal , After for medicine ten days ,and killed the mice. Observation mice body's weight change, Appetite change, Tumor volume and weight change, Observes and compares each treatment group using the method of immune histochmi stry the cancer gene and damps the cancer gene expression change.Result: Chinese drug and chemotherapy union group mice body weight change,The appetite change is smallest, The tumor volume and the weight change slightly, The biggest to the cancer gene inhibitory action, Damps the cancer gene expression to be most, Is higher than the Chinese medicine group, the chemotherapy group and the control group obviouslyConclusion: The Chinese drug unites the small dose chemotherapy medicine to have the remarkable inhibitory action to the mouse H22 hypodermic transplant lump, The Chinese medicine YMHJYGJ to chemotherapy effects has the remarkable improvement function, The prompt Chinese medicine YMHJYGJ product benefits the liver to fry has the anti-tumor and benefits to the chemotherapy medicine's poisonous efficiency, For clinical provides the reliable experim ental basis, has the clinical instruction value.