Quantitative Morphometric Analysis Of Thoraco-lumbar Vertebra Change Evaluate Danger Of The Osteoporosis Fracture

Objective:To study whether thoraco-lumbar vertebral-body shape change predict osteoporosis fracture and which items are sensitivity and practical.Methods:(1)A standard lateral thoraco-lumbar {T-L} spine radiography was done by centering the X-ray at L1.(2)Vertebral heights {anterior:Ha,middle:Hm and posterior:Hp},disc height {Hd} and 4 vertebral ratios {anterior wedging:Ha/Hp,central wedging:Hm/Hp,posterior wedging:Hp/Hpp and Hd/Ha} were assessed.Vertebral compression index {Hp-Ha/Hp Hp-Hm/Hp Hpp-Hp/Hpp} were also acquired.(3)Degree of severity of vertebral change was derived to 1;2;3;4 score when vertebral compression index was≥5%;≥10%;≥15% and≥20%.In all vertebral-body indexes at a certain vertebral-body,the greatest compression index was defined score at the vertebral-body.(4)Thoraco-lumber vertebral changes between the patients at 30—50 years old and≥60 were compared.Thoraco-lumber vertebral changes between the patients at 30—50 years old and≥60 with fragile fracture were compared.Thoraco-lumber vertebral changes at≥60 years old between with and without fragile fracture were compared.(5)In the 7 cases with BMD≤-2.5SD and without fragile fracture,8 cases with BMD normal and with fragile fracture,10 cases with BMD≤-2.5SD and fragile fracture,each other were compared.Results:(1)Vertebral changes at any levels of the thoraco-lumber spine deteriorate with increasing age.Hd/Ha and score were practical and sensitivity.(2)In the comparison between the patients at≥60 years old with and without fragile fracture thoraco-lumber vertebral changes were significant.(3)In the comparison between cases with BMD≤-2.5SD with and without fragile fracture,Hd/Ha and scores in the former were significant.Conclusion:Thoraco-lumber vertebral changes can predict fragile fracture.In all index, Hd/Ha and score were most significant.