Clinical Characteristics Of No-syndronmic Oligodontia

Objective:1.To determine the clinical type and inheritance mode of non-syndromic oligodontia.2.The number,constribution and abnormality of missing teeth and existent teeth were examined and analyzed,to explore clinical characteristics and condition of non-syndromic oligodontia.Method:The patients of no-syndromic oligodontia were selected and examined with oral cavity and system , then taken panoramic radiograph and analyzed statistical. We examined laboratory examination and took pedigree analysis.Result:1.36 no-syndromic oligodontia patients had been collected.8 congenital oligodontia families, which missing 363 teeth and 8 sporadic patients had been collected,which missing 115 teeth . To make sure the patients are accord with request by taking radiograph and careful examination.In the 8 families,there are 28 patients,which contain 15 males and 13 females. There were no significant diffierences in the number of missing teeth on maxilla and mandible nor on left and right sides between te two groups.2. In the 8 families,7 of them can be inherited as an autosomedominant and a ancestry with autosome-recessive.3. In the 28 congenital oligodontia patients,there are 23 patients have the abnormal existent teeth.But in the 8 sporadic oligodontia patients(82.1%),there are 3 patients. have the abnormal existent teeth(37.5%). we find the typical"peg shaped"teeth. There are many interspaces in the anterior teeth.4. There were no significant diffierences in microclement and alkaline phosphatase(ALP).5. After examining the oral health condition of 36 congential teeth agenesis patients,We can find that congenital teeth agenesis patients often accompanied adjacent caries (63.7%) ,malocclusion (77. 8% ) and periodontal disease(36.1).6. The congenital teeth agenesis is always accompanied by skull-jaw abnormity,classâ…¢dental malocclusion mal-occlusion.Conclusion:The congenital teeth agenesis maily is autosomal dominant inheritant disease. The inheritant appearance include the deleted tooth number and crown shape. Upper lateral incisors were most unstable in permanent dentition , and most tended to vary in teeth size , teeth morphology and teeth number during evolution. The developmental anomaly of teeth size , teeth morphology and teeth number might be a procedure of continuous variation and it might be different manifestation of the same mechanism.Congenital teeth agenesis influences oral health and occlusion.