The Relationship Between The Number Of Tooth Loss And The Incidence And The Severity Of Coronary Heart Disease In In-patients Of Department Of Cardiology:a Clinical Study

Objective:This study through the questionnaire survey to in-patients with coronary heart disease(CHD)and oral clinical examination,based on the results of coronary angiography to differentiate the severity of CHD,to explore the correlation between the number of tooth loss and the incidence and the severity of CHD.Methods:Totally 506 in-patients result from chest discomfort were involved in department of Cardiology of cardiovascular disease hospital of Shanxi Province,dating from May 2016 to November 2016.Basic information(age,gender,etc.),general condition(hypertension,diabetes,hyperlipidemia,etc.),smoking and oral health status(including calculus index,gingival index and the number of tooth loss)and oral health protection measures(brushing frequency and brushing time,etc.).Based on the inclusion criteria,finally 328 cases were included in the research,according to the results of coronary angiography,it can be divided into three groups:the non CHD group(degree of major vascular lumen diameter stenosis < 50%),the single lesion group,double or more lesions group.Using single factor and multi-factor ordinal logistic regression respectively,to analysis the relationship between the number of tooth loss and the incidence and severity of CHD.Results :1.In this study population,the proportion of hypertension,hyperlipidemia and diabeteswere 50%,47%,21.3%,significantly higher than the normal population prevalence of this disease.Comparison between the three groups in the baseline data: age,gender,smoking were statistically significant(P<0.05),but hypertension,hyperlipidemia,diabetes difference has no statistical significance(P>0.05);2.Oral index comparison between three groups,gingival index,the number of tooth loss were statistical significance(P<0.05),but between the three groups of calculus index,daily brushing frequency and brushing time difference has no statistical significance(P >0.05);3.Single factor ordinal logistic regression analysis indicated,the number of tooth loss is related to the incidence and the severity of CHD(1-5 vs 0: crude OR=2.143,95%CI:1.318-3.483,P=0.002;6-28 vs 0: crude OR=3.943,95%CI: 2.314-6.719,P<0.001);Other factors associated with the incidence and the severity of CHD include age,gender,smoking and gingival index(P<0.05);4.Multi-factor ordinal logistic regression analysis showed that adjusted social demographic variables(age and gender),system disease(hypertension,diabetes,hyperlipidemia),smoking,and gingival index respectively,the number of tooth loss is still an independent risk indicator of increasing the incidence and the severity of CHD.Compared with no tooth loss,when the number of tooth loss between 1-5,the risk increased 82.5%(adjusted OR=1.825,95% CI: 1.074-3.1,P=0.026),when the number of tooth loss exceeded five,the risk increased 1.65-fold(adjusted OR=2.65,95%CI:1.417-4.956,P=0.002).Secondly,age(adjusted OR=1.057,95%CI:1.03-1.085,P<0.001)and gender(adjusted OR=3.931,95%CI:2.067-7.475,P<0.001)were also the main factors influencing the incidence and increased severity of CHD(P < 0.05).Conclusion:1.In this in-patients,the proportion of hypertension,diabetes and hyperlipidemia was higher than the incidence of normal population;2.The number of tooth loss may be an independent risk indicator of increasing theincidence and the severity of CHD,and with the increasing of the number of tooth loss,the risk increasing;The risk increased with age;And the risk of men was greater than women;3.Periodontal disease is the main cause of tooth loss in the population,therefore,periodontal disease may be a significant risk factor to the incidence and the severity of CHD,and the number of tooth loss may be a simple but effective monitoring indicator.