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Experimental Study On The Influences Of Different Exercise Ways Of Osteoporosis, And Computer Simulation

Posted on:2009-05-02Degree:MasterType:Thesis
Country:ChinaCandidate:S L ZhaoFull Text:PDF
GTID:2144360242981177Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
With the development of society, the aging of the world population trends are becoming evident, osteoporosis incidence is also increased year by year. Osteoporosis occurs in the elderly, especially those in older women. Osteoporosis is the seventh in the world of the common diseases, is also plagued by the three major diseases of the elderly. Osteoporosis is bone loss, bone microstructure of degradation (cancellous bone thinning, fracture, the number reduced cortical bone porous, thinning) is characterized by brittle bones that fracture risk, as well as increased A general increase osteodystrophy, fractures and complications can be maimed, killed, the cost of the patients family and society heavy burden. These show that osteoporosis has become one of the diseases that have serious impacts on the quality of life of older persons.Bone mechanical environment directly affects bone growth, development and metabolism. Bone is by changing the mechanical environment to affect their metabolism and the prevention and treatment of various disorders. This is today's scientific research and clinical medicine in a hot, and the general call is exercise therapy. This paper exercise on bone from the angle of impact, adaptability to bone function and mechanical control theory, discusses different methods of movement of osteoporosis, and the establishment of the calculation model of osteoporosis. It can be divided into the following three parts:The first part is animal experiments. The experiment is the National Natural Science Fund "Osteoporosis mechanics - coupling between biological factors and Computer Simulation" experiments. The ovariectomized rats were divided into four categories: basic group, the control group castration, castration loading 2N group and castration loading 6N, as required daily living without injury dynamic loading, the determination of different groups rat damage loading, and discussed different loads on the tibia bone in ovariectomized rats in compact bone, cancellous bone elastic modulus of the impact of increased load, and the results show that the appropriate intensity can improve rat tibial bone structure mechanical properties.The second part is different effects of exercise on bone mineral density of the human experiments. Different ways and in accordance with the intensity of movement divided into four groups: control group, light intensity group, and larger intensity group and intensity group. Two years later, determinate the lumbar spine bone mineral density of 2-4 by measuring bone mineral density values, and discuss the different movements of the lumbar spine bone mineral density in the age group's changes, and compared the one year's and the two years'changes in bone mineral density. The results show that with the increase of age, the average decreased bone mineral density, and strength in the group was smaller than the declining trend in other groups, and sports safety, no side effects. Strength in the campaign mode is suitable for the elderly.The third part is based on the function of bone adaptability and mechanical control system theory, following the physiological process of bone remodeling, putting forward a time course of the description of cancellous bone osteoporosis process model to simulate the different exercise intensities due to waste caused by osteoporosis, and discussed the different peak bone mass of cancellous bone osteoporosis simulation of the process. The results showed that the larger exercise intensity can be reduced porosity reduction, and relieve the waste caused by osteoporosis; peak bone mass on the impact on osteoporosis is significant, greater peak bone mass can prevent osteoporosis.
Keywords/Search Tags:Sports, Osteoporosis, Ovariectomized rats, Bone density, Computer simulation
PDF Full Text Request
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