Application Of Brachial Ankle Pulse Wave Velocity In High Cardiovascular Risk Patients Of Uygur In Xinjiang

Objective To observe the relationship between brachial ankle pulse wave velocity (baPWV) and cardiovascular riskfactors as well as clinical cardiovascular events in high cardiovascular risk patients of Uygur. Methods Relevant clinical data, including baPWV, height, weight, waist circumference, blood pressure, heart rate, history and blood biochemistry test were collected in 148 consecutive patients with high cardiovascular risk. The number of riskfactors and cardiovascular events between patients with high baPWV (≥1700cm/s) and low baPWV (<1700cm/s) were compared. The data are analyzed by t-test,χ2-test, logistic regression with SPSS software version 13.0. A value of P<0.05 was considered significant in double-sided tests. Results Compared with low baPWV group, the cardiovascular events and the number of cardiovascular risk factors were higher in high baPWV group (46.8% versus 73.9%, P<0.01 and (3.8±1.0) versus (4.7±1.1), P<0.001, respectively). There is no statistical significance between two groups of sex, weight, body mass index, diastolic pressure, blood sugar, cholesterolemia and triglyceride, etc. The factors influencing baPWV were age (OR=5.111, 95%CI, 1.203-21.710, P<0.001), systolic blood pressure (OR=3.998, 95%CI, 1.739-9.198, P<0.01) and Pulse pressure (OR=2.711, 95%CI, 1.010～6.176, P<0.05). Conclusion In patients with high cardiovascular risk, the cardiovascular events and the number of risk factors were more frequent in patients with higher baPWV. Age, systolic blood pressure and Pulse pressure are independent risk factors of baPWV.