The Clinical Study Of Comparison Of Coronary Artery Lesion Between Han Nationality And Uygur Nationality Patients With Coronary Artery Disease

Objective:To study difference of coronary artery lesion between Han nationality and Uygur nationality patients with coronary artery disease Methods:2008 patients with coronary artery disease were analyzed retrospectively in our hospital between January 2005 and March 2008. According to different nationality, they were divided into two groups: Uyghur group (1041 cases) and Han group (967 cases). The coronary artery lesion was evaluated by the number, location, type of coronary lesion and Gensini scores. Results: 1) Compared with the Han Nationality homogeneity, Uygur nationality patients with coronary artery disease had higher prevalence rates of dyslipidemia and myocardial infarction, but lower prevalence rate of hypertension. Prevalence rate of Diabetes was higher in Uygur nationality female patients. In two nationalities, prevalence rates of hypertension and diabetes in the female patients with coronary artery disease were higher than that in the male group, but prevalence rate of dyslipidemia was exceptionally lower than that in the male group. The differences had statistical significance (P<0.05); 2) The involved types of coronary angiography were right coronary dominance, left coronary dominance and balanced type in a descending order in both Han nationality and Uygur nationality patients; 3) The involved coronary artery lesions were left anterior descending branch , right coronary artery, left circumflex branch and left main coronary artery in a descending order in both Han nationality and Uygur nationality patients; 4) A type rate was the highest in both Han nationality and Uygur nationality patients. Compared with the Han nationality patients with coronary artery disease, C type rate in the Uygur nationality patients was higher, B type rate in Uygur nationality female patients was higher than that in the Han nationality female patients, the difference had statistical significance (P<0.05); 5) The incidences of three-vessel disease and double-vessel disease of Han nationality patient were significantly lower than that of Uygur nationality in both male (39.0% vs. 42.6% and 36.0% vs.30.2% respectively) and female patients (28.5% vs. 36.5% and 24.0% vs. 27.5% respectively ), P<0.05; 6) Along with the age increasing, the single-vessel disease reduced and three-vessel disease increased gradually. There was an age-dependent Gensini scores increase in both Uygur and Han patients, and it increased more obviously after 50 years old. Gensini scores of Uygur patients were significantly higher than those of Han patients in same age groups. Conclusions: 1) Severity of coronary artery disease increased with age, single-vessel lesion gradually reduced and three-vascular lesion gradually increased. Severity of coronary artery lesion in male patients were significantly more serious than those of the same age section of female patients; 2) The coronary artery lesions of Uygur patients with coronary artery disease were more severe than those of Han patients in same sex and same age: more three-branch lesion and more C type lesion cases; 3) Compared with Han nationatity patients with coronary artery disease, morbidity age of similarly degree coronary atherosclerosis in the Uygur nationality patients may be more early.