Clinical Analysis Of 33 Cases Of Generalized Pustular Psoriasis

Objective: To discuss and analyse generalized pustular psoriasis patients' causitive factors, clinical manifestations, some relative laboratory examinations and five kind of different treatments. Methods: Through collecting 33 cases of generalized pustular psoriasis patients who lived in my dermatological department from 1993 to 2006, retrospective analysis of generalized pustular psoriasis' variable causitive factors and their percents, clinical manifestations, especially accompanied with systemic symptoms, some relative laboratory examinations and the comparation of five kind of different treatments. Results: In our patients, the most of them have no causitive factor, except for it, the inflammation and the improper use of corticosteriod are very common. In clinical manifest -ations, except for characteristic clinical manifestations that are aseptic pustulars from pinpoint to millet, it is frequently accompanied with systemic symptoms, espicially fever. In the relative laboratory examinations, the increase of leucocyte and neutrophils, the decrease of red blood cell, albumin and calcium is the most common. Five kind of treatments should be selected according to the severity of disease. Conclusions: Causitive factors of generalized pustular psoriasis are variable; its systemic symptoms are very common, except for its characteristic eruption; its results of several kind of laboratory examinations are abnormal; its treatments should be choosed according to the severity of disease, the use of corticosteriod should be cautious.