The Study Of Kunshen Granule In Treating Progressive Gastric Carcinoma In Clinic And It's Effect On MVD Of Carcinomatous Rats Experimentally Induced

Objective: Study the effect and principle of Kunshen Granule in treating progressive gastric carcinoma. Methods: 1. Clinical study: 60 patients who accorded with the diagnosis standard were separated to Kunshen Granule group and Shenlian Capsule group at random. We observed the clinical therapy result and compared the death rate of two groups. 2. Experimental study: Oral administration of MNNG to Wister rats resulted in a high incidence of gastric carcinoma. The rats were separated into six groups at random, negative control group, model group, positive control group, Kunshen large dose group, medium dose group and small dose group dose. After administration, we compared the count of microvessel density (MVD) of the six groups. Results: The clinical research proved that the effective rate of Kunshen Granule group was obviously higher than that of Shenlian Capsule group (P<0.05) and the therapy integral was lower than the Shenlian Capsule (P<0.05). The experimental research proved that Kunshen Granule could decline the MVD of carcinomatous rats experimentally induced. Conclusion: Kunshen Granule can decline the MVD of gastric carcinoma and treat the gastric carcinoma effectively.