Objective: To summarize the procedure and clinical value of the application of local resection with the guidance of preoperation indwelling wire placed through puncture under X-ray or CT scan in treatment of nonpalpable but mammography or CT demonstrated small breast lesions. Methods: Operation of local resection was done in patients with suspected small lesions founded by mammography or CT scan, which could not be palpabled clinically, demonstrated signs such as clusters of microcalcifications, small nodules or regional structural irregularities. After puncture under X-ray or CT of the lesion was done, a guide wire was indwelled in the suspected spot. With the guidance of the wire, surgical resection of the suspected tissue was made. Result: 72 of 58 patients were punctured successfully only one time. 50 lesions were found and punctured under X-ray, including clusters of microcalcifications (28 lesions),small nodules (20 lesions) and regional structural irregulatities (2 lesions).22 lesions were found and punctured under CT scan, including clusters of microcalcifications (5 lesions), small nodules (15 lesions)and regional structural irregulatities (2 lesions). Pathological results showed malignant in 5 lesions(5 patients), precancerous change 10 lesions (6 patients)and benign in 57 (47 patients). Conclusion: Surgical resection with the guidance of indwelling wire placed through puncture is very helpful in correctly localizing and removing small latent breast lesions. The technique is a reliable and useful approach to surgical practive with less invasive and easy performing, and is very helpful for the diagnosis of breast lesions.
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