| Objective To elucidate the diagnostic value of quantitative analysis of plasma EBV–DNA in patients with nasopharyngeal carcinoma.Methods Using fluorescence quantitative polymerase chain reaction(FQ-PCR),the copies of EBV–DNA in 35 plasma samples of NPC patients were examined, and compared with 50 normal controls.Results The positive percentage and copies of plasma EBV–DNA of NPC patients(65.7%,Median17 180.0) were significantly higher than those of normal controls(32.0%,Median0).Conclusions FQ-PCR determination of plasma EBV–DNA still can not make a definite diagnosis to NPC,but it is of practical use to screen NPC.Our results suggest that further investigation is warranted.
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