| Objective To study①study the festure in epidemiology of measles between 1994 and 2005 in Taiyuan ,②trabant sampling inspection 200 women range 18 to 38 years old . 200 pairs pregnant women and its newborn,200 infants range 5 to 8 months, examines respectively the measles-specific interferon gamma+ in their blood serum ,to analyze fhe influencing facfor to material antibody and the correlation factor of measles maternal antibody deliver and fade away related factor of the half- life.③compares the measles vaccine immunity success rate for the infants 5-8 months.for studding time that infant begin to vaccine the measles vaccine.Methods Adopt retrospective epidemiology method to Analyze the measles cases in 1994～2005 year for its Epidemiology characteristic and the reason to cause the measles.sampling inspection 200 women range 18 to 38 years old , 200 pairs pregnant women and its newborn.200 infants range 5 to 8 months, carry on studying as follows:①to test the measles-specific interferon gamma+(IgG) in their blood serum using ELISA method.②to compare antibody titre of infant with his mother's , and relation between them,③to observe immune response of infants in 5～8 months after vaccinating measles vaccinerespectively.④statistics analysis in Microsoft Excel 2003 and SPSS 10.0 for windows.Results1. The main epidemiology characteristic of measles in 1994～2005: the epidemic cycle was estended ,the reason was winter and spring, the time of measles epidemic is 5～8 months. Gujiao,Yingze,Xinghualing attack rate higher,Less than 1 year old infant were highest. Occasionally measles outbreak appeard in adult,the reason is that the person of blank immunization accumulated in countryside and population flow.2. Antibody level of newborn accords woth his mother and women in 18～35 years old.3. Antibody positive rate of newborn is much higher than it of 5～8 months age.the Maternal Antibody positive rate and GMT were decreased with the month age increasing.4. after immunizing measles vaccine first time between 5 and 8 months old infants, successful rares were different with the of month' age and the maternal antibody. The monthis is more order. The antibody titre lever is more lower, the successful rares of immunization is more higher, the immune response is the highest in eight months age.Conclusions 1. The primary measles vaccination had better 8 months age,and revaccinated at 18～24 months old ,second measles vaccination; the prim ary measles vaccination may be advanced to the age of 6 months durante measles epidemic outbreak..women who to apply for marry immunize measles vaccine,in order to raise maternal antibody and it's remaining time. Thereby depress the attack rate of infant.2. Enhance for the control of measles preferably include the improvement of the rate of conventional inoculation, strengthening of population flow management and eradication of blank immunization.,improving whole immunization level.3. Checking document of vaccination in primary school, middle school, university and strengthen management including no vaccined, population (low, countryside especially. They must medical examination and register ,then immunizing measles vaccine or measle-rubella vaccine or measle-mumps-rubella vaccine under normally medical examination.4. It can avoid measles outbreak we carry out emergency immunity in time. Once discovertendency of measles outbreak.
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