Study And Survey On Patients With HIV/HCV Co-infection In Shenzhen Area

Objective: To determine the status of HIV/HCV co-infection in Shenzhen area and explore its risky factors among them.Methods: To investigate the rate of co-infection with HCV among HIV infected person, demographic characteristic, drug use behavior, sexual behavior, and serum specimens were collected and analyzed for HCV and HIV viral load, T lymphocyte counts and liver function in HIV/HCV co-infected person, from which the statistical analysis was performed by SPSS.Results: There are 55 HIV/HCV co-infected persons in 205 HIV infected people. The rate of co-infection with HCV among HIV infected is 26.8%. During them, 83.3% was unemployed, 79.2% was unmarried and 58.2% was intravenous drug users in the HIV/HCV co-infected persons. There was statistical negative correlationship between CD4 cell counts and HCV viral load and HIV viral load. The HIV/HCV co-infected persons had increased HCV viral loads and lower CD4 cell counts than the single HCV infected (P <0.05), had increased ALT levels and lower ALB levels than the single HIV infected (P <0.05).Conclusions: HIV/HCV co-infected patients in Shenzhen area takes 26.8% among HIV patients; prerequisite of HIV/HCV co-infection is people in young age, with unstabel occupation and single in marriage. users with intravenous drug addition, using insanitary equipment and having sexual behavior were the high-risk group. HIV/HCV co-infection interferes viral nucleic acid, influences cell immune system CD4 cell immunity levels and promotes HCV in HTVTHCV co-infection.