Objective: To compare of the short -term and long - term curative effect of different therapies in the elderly with coronary artery disease.Methods: To analyse 197 eases of registered patients 75 years' elderly (from 2003 to 2006) with coronary artery disease. Coronary artery disease patients were divided into three groups: drug therapy group (64), percutaneous coronary intervention(PCI) group(77) and coronary artery bypass graft(CABG) group(56). Follow-up the elderly patients of 138 cases, the rate of follow-up were 70%. The major adverse cardiac events including death, myocardial infaretion(MI) and revaseularization(PCI or CABG) was observed through follow-up.Results: Short term mortality in CABG group was higher than that in the PCI and drug therapy groups (P<0.05), with no obvious difference observed between the latter two groups (P>0.05). Long term mortality in PCI group is lower than drug therapy group(P<0.05), meanwhile in CABG group is lower than drug therapy group, but no obvious difference observed between the above two groups(P>0.05), and no obvious difference observed between the PCI + CABG groups(P>0.05); the revascularization rate of the CABG group ranked the lowest(P<0.05), and no obvious difference observed between the PCI + drug therapy groups(P>0.05); LVEF it was lowest in drug therapy group than that in the other two groups(P>0.05), with no obvious difference observed between the PCI + CABG groups(P>0.05); the heart failure rate of the drug therapy group ranked he highest (P<0.05), and no obvious difference observed between the PCI + CABG groups (P>0.05). Short-term and long-term recurrence of myocardial infarction had no difference between the CABG, PCI and drag therapy groups.Conclusions: 1. Coronary revascularization may improve the long-term survival rate of patients: 2. Percutaneous coronary intervention (PCI) can be done in the elderly with low short term mortality rate, high achievement ratio of operation and few complications. 3. Coronary artery bypass graft (CABG) degrades recurrence of revascularization of elderly patients with coronary artery disease 4. Coronary revascularization can elevate LVEF and significantly improve the heart function.
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