Short-term Clinical Outcomes After Hybrid Coronary Revascularization Versus Off-pump Coronary Artery Bypass For The Treatment Of Multivessel Or Left Main Coronary Artery Disease

Background Hybrid coronary revascularization（HCR）and off-pump coronary artery bypass grafting（OPCABG）are both considered to be safe,feasible,less invasive techniques for coronary revascularization.While both procedures utilize the left internal mammary artery（LIMA）to left anterior descending artery（LAD）graft,HCR selects drug-eluting stents（DES）instead of saphenous vein bypass.It remains unclear whether HCR is equal to,better or worse than OPCABG.Methods and Results Meta-analysis was conducted using a random effects model.Seven observational studies were included.There was no significant difference either in in-hospital Mortality（RR 0.57,95%CI 0.13-2.59,p=0.47）or in MACCE rate（RR 0.63,95%CI 0.24-1.64,p=0.34）between the HCR group and the OPCABG group.Significant difference was observed between the two groups in the length of hospitalization（RR 0.55,95%CI 0.13-0.97,p=0.01）,length of ICU stay（RR 0₄5,95%CI 0.10-0.80,p<0.05）,intubation time（RR 0.48,95%CI 0.13-0.84,p<0.01）,need for red blood transfusion（RR 0.67,95%CI 0.56-0.82,p<0.001）,and total in-hospital costs（RR 0.90,95%CI 0.39-1.42,p<0.01）.Conclusions Compared with OPCABG,HCR did not improve early survival but decreased the length of hospitalization,length of ICU stay,intubation time,need for red blood transfusion,and increased total in-hospital costs。...