Study On Quality Of Life And Influencing Factors Of Patients With Acute Myocardial Infarction Before And After PCI

Objective1. To understand the effect of PCI on quality of life of patients with acute myocardial infartion(AMI) through evaluating the life quality of patients with AMI undergone PCI or not at admission, at discharge and post discharge.2. To determine the factors that influenced the quality of life of patients with AMI undergone PCI.MethodA controlled clinic trail was designed. 129 participants with AMI were selected from the first, second, third Xiangya hospital of central south university, central hospital of Changsha and Hunan People's hospital during January 2006 to March 2007. There were 66 patients in PCI group and 63 patients in non-PCI group. Common information and Myocardial infarction dimensional assessment scale (MIDAS ) questionnaire survey were performed in all the participants at admission, at discharge and 3 to 6 months post discharge. All the data were analyzed using SPSS 11.0 software. Descriptive statistical analysis, T test, 1-way ANOVA analysis and multiple linear regression analysis were performed in this study.Result:1. The questionnaires wrer sent to participants in three stages. At last 207 questionnaires were sent to the participants of PCI group, among which 198 questionnaires (95.6%) were valid. 204 questionnaires were sent to patients of non-PCI group, among which 189 (92.6%) were valid.2. Intra-group comparisons: In PCI group, the life quality MIDAS score at discharge was significantly different when compared with that at admission and 3 to 6 months post discharge (P<0.05). In non-PCI group, the life quality MIDAS score at discharge was significantly improved in comparison to that at admission (P<0.05), while there were no significant difference existed between that at discharge and 3 to 6 months post discharge (P>0.05).3. Inter-group comparisons: the life quality MIDAS score of PCI group at admission was not significantly different from that of non-PCI group at admission (P>0.05); the life quality MIDAS score at discharge were not different between PCI and non-PCI group with regard to patients with normal heart function at admission (P>0.05), while such a difference exist between the two groups with regard to patients with heart failure at admission (P<0.05); After discharge in 3-6 months, there is a significant difference among the patients who were treated more than 6 hours after AMI and complicated with heart failure. (P<0.05). There is no significant difference among the patients treated in 6 hours or more than 6 hours but without complication of heart failure in both groups (P>0.05).4. Variations of the life quality MIDAS score between prior to and post discharge were significantly different in PCI group compared with that of non-PCI group (P<0.05).5. Whether complicated with heart failure or not and age were the major factors that influenced the life quality of patients of PCI group at admission. Sex was major factor that influenced the life quality at discharge, while compliance was the major factor that influenced the life quality of PCI group 3 to 6 months post discharge.Conclusion:1. Both PCI and non-PCI therapy can improve the life quality of patients with AMI at discharge, while PCI have more significant effect than non-PCI therapy.2. PCI can improve the life quality of AMI patients 3 to 6 months post discharge, while non-PCI therapy has no such effect.3. As compared with non-PCI therapy, PCI can significantly improve the life quality of AMI patients complicated with heart failure at admission.4. Whether complicated with heart failure or not and age were the major factors that influenced the life quality of patients of PCI group at admission. Sex was major factor that influenced the life quality at discharge, while compliance was the major factor that influenced the life quality of PCI group 3 to 6 months post discharge.