| Objective:Recently a baseline glucose level on admission is announced as a factor of poor outcomes in both short-terms and long-terms in acute myocardial infarction(AMI) patients.Now we are trying to assess the influence of admission blood glucose levels on prognosis of Chinese patients with acute ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention(PCI).Method:176 consecutive patients who arrived in our hospital in the first 24 hours from the chest pain beginning and were treated with PCI for STEMI were analyzed.The grouping criterion was the blood glucose level on admission[threshold≥7.8 mmol/L (140 mg/dL)].We compared the two groups' rates of one year combined clinical end events,which including heart failure,unstable angina,MACE(Major Adverse Cardiovascular Events,MACE ),trying to find out the relationships between the blood glucose on admission and the prognosis of AMI patients.Results:One year rates of combined clinical end events was significant different between the groups:5.95%for admission blood glucose of＜7.8mmol/L and 17.39%for admission blood glucose of≥7.8mmol/L(P=0.021).Multivariate analysis revealed blood glucose level on admission was a factor affecting 1-year rates of combined clinical end events.Creatine Phosphokinase(CPK),MB isoenzyme of creatine dinase(CK-MB),Body Mass Index(BMI) were also a factor influencing the prognosis of the patients.CPK,CKMB,BMI were noted 861.93±915.74IU/L;57.47±86.04 IU/L; 22.02±2.36 Kg/m2 separately for admission blood glucose of＜7.8mmol/L and 1900. 18IU/L±2301.92 IU/L;88.44±113.35IU/L;23.71±3.08 Kg/m~2 separately,for admission blood glucose of≥7.8mmol/L(CPK:P＜0.001;CK-MB:P=0.042;BMI:P＜0.001).Conclusion:Elevated admission blood glucose levels in STEMI maybe affect the prognosis of patients treated with PCI,and the CPK,CK-MB,BMI may one of the mediate factor during the course. |
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