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Clinical Trial On Treating Chronic Hepatitis B Of Liver-spleen Dampness-heat Type With The Method Of Jianpi Qingre Treatment

Posted on:2008-11-09Degree:MasterType:Thesis
Country:ChinaCandidate:M ZhaoFull Text:PDF
GTID:2144360215465364Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Hepatitis B virus (HBV) infection is a crisis of global human health disease.According to a nationwide survey of prevalence of sexually transmitteddiseases, my crowd HBV infection rates as high as 60%. About 120 million chroniccarriers, accounting for 10% of the population. How is the treatment of chronichepatitis B worldwide scholars have concerns.With thousands of years of Chinese medicine and the fight against infectiousdisease history, family medical history, in theory and clinical practice, hasmade a significant contribution. Many doctors in clinical treatment andresearch found that liver and spleen two dirty incidence of chronic hepatitisB is an important organ. Hygrothermal capsici its incidence is an importantfactor. Lingnan region against special climate characteristics, clinical datacollection, we found that liver and spleen volume is damp-heat in 1993, withresearch value.Objective: This study was to review the literature on the theoretical basis,conclude my digestive and medical treatment of chronic hepatitis B clinicalexperience, combined with modern medicine and pharmacology study resultsrepresentative governance was formed Jianpi Qingre Lishi to the norms syndrome,under the guidance for the treatment of chronic hepatitis B to liver and spleenhumid certified clinical randomized controlled trials, and the clinic efficaof science, objective, reasonable observation analysis.Methods: According to the principle of random grouping, would have beendiagnosed as chronic hepatitis B patients with liver and spleen humid 60 by1:1 ratio were randomly divided into treatment and control groups. Treatmentgroup Jianpi Qingre Dampness Recipe developed; effectiveness of the controlgroup were given similar positive drug compound Yigan pill. Treatment for three months, the two groups were observed in patients with clinical symptoms andsigns, liver function, HBV changes and in the light of Chinese herbal medicinetreatment of viral hepatitis clinical research guiding principles of chronichepatitis B criteria compared the two drugs in the treatment.Results: The two groups total clinical efficacy of comparison : the treatmentgroup, the total efficiency of 90%; the control group, the total efficiencyof 85.7%, the total clinical efficacy of the two groups showed no significantdifference (P>0.05). The two groups after treatment than before has improved(P<0.01). Improvement in the treatment group with feces rare pond, torpidintake, heavy storm burnout syndrome better than the control group, the twogroups was statistically significant (P<0.01). Improved liver function twogroups: After treatment, ALT,AST,AKP,G,TBiL than before treatment wassignificantly improved (P<0.01); However, the two groups showed no significantdifference (P>0.05). 4. The two groups HBV markers detection indicators ofchange: for the treatment group HBsAg negative rate of 13.33%. HBeAg negativerate of 26.92%, 26.67% negative rate of HBV-DNA control group HBsAg negativerate of 0, HBeAg negative rate of 14.28%, HBV-DNA negative rate 21.43%. Treatmentand control groups showed no significant difference (P>0.05). 5. Comparedtoxicity:there were no adverse reactions and side effects.Concludes: Jianpi Qingre treatment of liver and spleen Lee wet humid Syndrome,achieving better results. On the side of patients with chronic hepatitis Bimproved to a certain extent syndrome, restoring liver function. From overallplay and certainly Baogan JiangMei virus. Application Jianpi Qingre Lishi tothe treatment of chronic hepatitis B liver and spleen dampheatsyndrome cansignificantly improve the clinicalsymptoms, especially in improving patientsburnout heavy storm, torpid intake, feces and other rare pond syndrome betterthan the control group. Results show Jianpi Qingre Lishi to treatment ofchronic hepatitis B liver and spleen humid permit a better Jianpi Yiqi role.The results indicate wet Jianpi Qingre prescription benefit in the treatmentof chronic hepatitis B patients, the process and outcome. Significantly reducepatients with those signs and symptoms, improve liver function.
Keywords/Search Tags:Jianpi QingreLishi side, Chronic hepatitis B, Hepatosplenic humid type, Clinical Study
PDF Full Text Request
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