Clinical Analysis Of 61 Cases With Cancer And Thrombosis Disease

BackgroundThrombosis disease is a common complication of malignant disease process. The incidence of malignant tumors with thrombosis diseases remains high; the detection rate of thrombosis diseases in the follow-up cancer is higher. Thrombosis involves in tumor progression, angiogenesis and metastasis. Anticoagulant therapy is not only effective in the treatment of thrombosis, but also has anti-tumor effect. Therefore, thrombosis disease associated with cancer attracts clinical widespread attention. The early discovery, correct diagnosis and energetic treatment can improve the overall quality of life and prognosis of patients.MethodWe retrospectively analyzed 61 cases of cancer with thrombosis disease, which had been treated in our hospital from 2003 to 2006. The analysis content had risk factors, diagnosis, treatment and prognosis. We used Logistic regression to evaluate the risk factors, used x~2 test to evaluate the effect of thrombolytic therapy, and used Kaplan-Meier analysis to analyze survival rate of the patient group and control group for comparison. Result This study found that many factors, such as tumor types and clinical stages, complications, surgery, chemotherapy, radiotherapy, endocrine therapy, and other measures for the treatment, can promote the cancer patients to concurrence with thrombosis disease. And the prognosis is poor. They were diagnosed by the clinical manifestation, color Doppler ultrasound, CT and magnetic resonance imaging examinations and laboratory tests. The major therapeutic measures included surgery, thrombolysis and anticoagulation, antiplatelet, basic treatment and so on. The early discovery, correct diagnosis and energetic treatment, especially early application of thrombolytic therapy, can improve the overall quality of life and prognosis of patients.Conclusion1. The infection, surgery, chemotherapy, blood transfusion and the use of DEX can obviously promote the cancer patients to concurrence with thrombosis disease.2. The early discovery, correct diagnosis and energetic treatment, especially early application of thrombolytic therapy, can improve the overall quality of life and prognosis of patients.3. The prognosis of the cancer patients with thrombosis disease is poor.