Frozen Section And Surgical Margin To Predict The Prognosis Of Laryngeal Carcinoma After Partial Laryngectomy

Background: Carcinoma of larynx is one of the most common malignant tumors in Department of Otorhinolaryngology. In recent years, the incidence of Carcinoma of larynx has increased rapidly. Various treatments have been used to treat Carcinoma of larynx, but surgery is the most effective way. And Partial laryngectomy is considered to be the best surgery manner to retain the function of the larynx. But to the Partial laryngectomy, the problem is to decide the surgical margin because of the balance between the function of the larynx and the recurrence rate of cancer.Method: 77 cases of laryngocarcinoma were reviewed in this retrospective study. All of the laryngocarcinoma patients were treated in the Sir Run Run Shao Hospital during 1996. 1.1～2001.12.31. Frozen section, surgical margin, and pathological section were compared to the recurrence rate of cancer, the survival rate of patients and the evaluation of further air duct quality.Results:The Partial laryngectomy can not only improve the survival rate of patients, but also retain the function of the larynx. To those Partial laryngectomy whose surgical marginare larger than 0.5cm, whether carrying out the frozen section is not significant. But to those Partial laryngectomy whose surgical margin are smaller than 0.5cm, we should carry out the surgical margin to decrease the positive rate of the pathological section. Recurrent rate of the negative group is lower than the positive group. Carrying out the frozen section can decrease the recurrent rate of the laryngocancimoma and improve the survival rate of patients, but not influence the evaluation of further air duct quality.