IL-8 Levels In Expressed Prostate Secretion Of BPH With Chronic Prostatitis

Objective: To investigate the levels of the anti-inflammatory cytokine IL-8 in expressed prostate secretion(EPS) of BPH with chronic prostatitis. To study the sensitivity and specificity of the IL-8 in EPS identifying benign prostate hyperplasia(BPH) with chronic prostatitis from the simply BPH when comparing with the pathologic diagnosis. To research the incidence of chronic prostatitis of the patients with BPH, and we are going to make detailed description of these chronic prostatitis. We also will explore the relationship of IL-8 in EPS with WBC/HP,urinary tube and age.Method: The study included 44 patients with BPH admitting into our department during November , 2004 to June , 2005 for operational therpy. Before TURP operation, we gained the EPS by prostate massage to measure cytokine IL-8 with Enzyme-linked immunosorbent assays ,and test WBC count. After the operation, we took pathological section from our department of pathology to study them again by an experienced pathologist.Results: IL-8 was detectable in all patients(threshold of detection for IL-8...