The Prevention Of Postoperative Acute Thomboembolism

Purpose: To observe the change of hemorheology, blood fat , bloodclotting index to study the prevention of the perioperative acute thromboembolic disease for the patients with thromboembolic risk factors. Method: Collect totally May in 2006 from 2005 September — 80 surgery patients is divided into four groups: dextran-40( n=20 ),daxtran + danshinone( n=20 ), anthemorrhagic( n=20 ),no interfere set ( n=20 ).By observing all indexes .compared allpatientd with the change between the preoperative period to postoperative period and reviewed the postoperative thomboembolic events. Result: (1)The postoperative whole blood viscosity, the whole blood reduce viscosity(low-share rate)and TT led to significant decrease in the group of dextran ; In the group of dextran and danshinone , the decrease in the whole blood viscosity , the whole blood reduced viscosity and PT ,APTT were definitely marked at postoperative period than preoperative period ;All these indexes in the third group didn' t change, beside TT; In the forth group , postoperative the whole blood viscosity , the whole blood reduced viscosity, RBC aggregation and TT were much lower than preoperative period .All the indexes of blood fat were decrease in the former three group .Comparing HDL-C with the perioperation , only last tow group were decrease. Conclusion: (1) The dextran and danshinone are profit to prevent the perioperative acute thomboembolic disease. (2)It should be carefully use anthemorrhagic , although hemorheology index didn' t change.