| Objective:To explor the therapeutic effect and mechanism of warming and tonifying the spleen and kidney in treating Deficiency of spleen yang and kidney yang Syndrome of Irritable bowel Syndrome, IBS.Methods:60 cases of IBS were divided into two groups randomly.The treatment group of 30 cases was treated with warming and tonifying the spleen and kidney while the control group of 30 cases was treated with Guchang Zhixie Wan . Symptoms and signs of eath group were observed before and after the treatment in cluding IBS and pathologic observing.Results:The treatment group was much better than the control group in improving clinical symptoms and signs, promoting recoverment of pathological changes.The differents was significant in statistics(P<0.05).Conclusion:warming the middle-energizer and invigorating deficiency is effective treatment for IBS.The mechanism might be related to promoting intestines function, promote intestines mucosa flatness muscle cellular's electricity physiology science, and small intestine transfer movement complex wave;To influence anus inner constrictor pressment ,and recta inner pressment, improve threshold of ache from intestines outstretched. |