Changes Of Endocrine Hormones In Children With Attention Deficit Hyperactivity Disorder

Objective To examine the changes of thyroid hormone(TH),thyroid-stimulating hormone (TSH),prolactin (PRL),estrogen(E₂),testosterone(T) in childhood with attention deficit hyperactivity disorder (ADHD).Methods The 32 ADHD children were divided into three groups , identified 19 ADHD-Combined type(ADHD-C),9 ADHD-Predominantly inattention type(ADHD-I),4 ADHD-Predominantly hyperactive-impulsive type(ADHD-HI). 15 normal controls were recruited. The serum levels of TH,TSH,PRL,E₂,T were determined with automated–chemoluminescence method.Results (1) The levels of free triiodothyrone(FT₃) in groups of ADHD and its subtypes were in normal range ,but were obviously highter than that of controls(P<0.05). The level of triiodothyron(eT₃)in the group of ADHD was in normal range ,but was obviously highter than that of controls(P<0.05). Thyroxine(T₄) in the group of ADHD-I was in normal range, but it was obviously lower than that of controls(P<0.05). The levels of T₄,free thyroxine (FT₄ )in the group of ADHD-I were lower than that of ADHD-C (p<0.05) . The levels of TH were no significant different between the groups of ADHD-I and ADHD-HI,so do the groups of ADHD-HI and ADHD-C .(2) There was no significant different in the level of TSH in the...