The Rationing Analyse Of Microprimetry In Eyes With Diabetic Retinopathy

Objective: Evaluation of mean light sensitivity and fixation stability in diabetic patients with or without diabetic retinopathy to investigate early diagnosis of diabetic retinopathy and clinical significance of diabetic retinopathy by using microprimetry (MP1).Methods: We studied 21 diabetic patients (42 eyes) without retinopathy (NDR group), 31 diabetic patients (43 eyes) with retinopathy (DR group) and 30 healthy volunteers matched with age. The visual acuity, 2° mean light sensitivity, 12° mean light sensitivity, fixation stability and central fixation were measured. At the same time, the light sensitivity of the various stages, the various pathological changes and the various areas in posterior pole of diabetic retinopathy were compared.Results: There was no significant differences in visual acuity of NDR group(P>0.05), but the visual acuity of DR group was significantly diseased than in control group(P<0.01); the visual acuity of DR group was significantly diseased than NDR group(P<0.01). There were significant differences in mean light sensitivity, fixation stability and central fixation( P<0.001). The various pathological changes of DR group are, hard exudates(8.58±3.98 dB ), macular edema, (6.18 ±2.80 dB) soft exudates (4.84±2.72dB) and hemorrhage(3.02±5.01dB). There were no significant differences in mean light sensitivity of them(P>0.05).The mean light sensitivity of superior—temporal in posterior pole was significantly diseased than in superior —nasal and inferior—nasal(P<0.01). Linear correlation analysis showed that the 2° and 12 ° mean light sensitivity of DR group were not correlated with corrected visual acuity(r=0.36% 0.29, P>0.05). In DR group there was no significant differences in mean light sensitivity and visual acuity of various stages(P>0.05).Conclusion: It is suggested that examination of mean light sensitivity, fixation stability and central fixation has certain clinical significance in early diagnosis of diabetic retinopathy. Compare to other areas, the superior—temporal in posterior pole of DR more be damaged. There were no significant differences in mean light sensitivity of the various pathological changes. The mean light sensitivity of DR group was not correlated with corrected visual acuity. There was no significant differences in mean light sensitivity and visual acuity of various stages.